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What is hereditary nonpolyposis colorectal cancer (HNPCC)?

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Nonpolyposis colorectal cancer, or HNPCC, is the most common form of hereditary colon cancer, accounting for about 3% of all colorectal cancer diagnoses each year. People with HNPCC often have at least three family members and two generations with colorectal cancer, and cancer develops before age 50. Although not everyone who inherits the HNPCC gene will develop colorectal cancer, the risk is very high -- about 80%.

From: Inherited Colorectal Cancer WebMD Medical Reference

SOURCES: 

Cleveland Clinic.

The American Journal of Pathology : "Familial Adenomatous Polyposis-Associated Thyroid Cancer."

Reviewed by Minesh Khatri on March 14, 2019

SOURCES: 

Cleveland Clinic.

The American Journal of Pathology : "Familial Adenomatous Polyposis-Associated Thyroid Cancer."

Reviewed by Minesh Khatri on March 14, 2019

NEXT QUESTION:

How can a doctor determine if hereditary nonpolyposis colorectal cancer (HNPCC) is in your family history?

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