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How Long Does It Take to Detox From Oxycontin?

By Manjari Bansal
Medically Reviewed by Yilang Tang, MD, PhD on July 26, 2021
Are you or someone you love abusing Oxycontin? Learn how long detoxing from Oxycontin takes and how to get help.

Oxycontin is the brand name for a timed-release formulation of the opioid pain reliever oxycodone. Opioids are strong medications that can be addictive. If you or a loved one are addicted to Oxycontin, you may wonder how long it takes to detox from Oxycontin. Read on for more about what happens during Oxycontin detox and how to get help.

Detoxing from Oxycontin: What to Expect

If you or your loved one have determined that an oxycontin addiction is present, ending intake of the drug may be the first step in a recovery process. Stopping the use of an opioid that your body has become addicted to can cause unpleasant physical symptoms known as withdrawal. 

Oxycontin withdrawal symptoms may start as early as 4 to 8 hours after the last dose. Early withdrawal signs may manifest as flu-like symptoms, with typical opioid withdrawal symptoms showing up later.

Detoxing from oxycontin may take 1 to 2 weeks, with most acute symptoms clearing up in about 3 days and the rest of the symptoms in 2 or more weeks.

Detox Programs

In detox programs, the duration of a complete detox depends on many factors such as “the type of the protocol used by every program, the strength of the drug used, the severity of patient's disease and symptoms, and the response to the treatment,” Fariba Miryousefi, MD, an addiction medicine specialist and Chief of St. Elizabeth's Comprehensive Addiction Program in Massachusetts, tells WebMD Connect to Care.

Individuals opting for detox programs are often physically, psychologically, and emotionally evaluated to determine their fitness for entering treatment programs. “Most programs require a medical clearance, [meaning] that patients need to be evaluated by a physician to confirm they are healthy enough to undergo the detox process,” Miryousefi says.

"Detox treatment often involves the use of different medications to relieve withdrawal symptoms. “Opioid agonists or medications with a similar action to opioids are used along with other medications to treat the uncomfortable symptoms associated with withdrawals,” Miryousefi says.

However, according to the National Institute on Drug Abuse, detoxification may not be sufficient enough to treat opioid addiction. “Detox is the first step in a journey called recovery. Patients should seek psychosocial treatment and/or medication-assisted treatment after safely withdrawing from the drug,” Miryousefi says.

The American Medical Association says that medication-assisted treatment, or MAT, is an effective treatment for individuals experiencing opioid addiction. Three FDA-approved medications commonly used to treat opioid addiction are methadone, buprenorphine, and naltrexone.

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