PREVIOUS QUESTION:

 

NEXT QUESTION:

 

How are tricyclic antidepressants used as antidepressants?

ANSWER

Tricyclic antidepressants (TCAs) include amitriptyline (Elavil), desipramine (Norpramin), imipramine (Tofranil), and nortriptyline (Pamelor). Like reuptake inhibitors, tricyclics seem to block the reabsorption of serotonin and epinephrine back into nerve cells after these chemicals are released into a synapse. Because of the potential side effects, your doctor might periodically check your blood pressure, request an EKG, or recommend occasional blood tests to monitor the level of tricyclics in your system. These medicines might not be safe for people with certain heart rhythm problems.

SOURCES:

News release, FDA.

Ian A. Cook, MD, director of the Depression Research Program, University of California Los Angeles.

Dean F. MacKinnon, MD, associate professor, the Johns Hopkins Hospital, Baltimore.

MedicineNet, "Antidepressants."

Medscape: “FDA Approvals: Symbyax and Edluar.”

National Institute of Mental Health Web site, "Depression."

Reviewed by Smitha Bhandari on June 27, 2019

SOURCES:

News release, FDA.

Ian A. Cook, MD, director of the Depression Research Program, University of California Los Angeles.

Dean F. MacKinnon, MD, associate professor, the Johns Hopkins Hospital, Baltimore.

MedicineNet, "Antidepressants."

Medscape: “FDA Approvals: Symbyax and Edluar.”

National Institute of Mental Health Web site, "Depression."

Reviewed by Smitha Bhandari on June 27, 2019

NEXT QUESTION:

How are monoamine oxidase inhibitors used as antidepressants?

WAS THIS ANSWER HELPFUL

"ALEXA, ASK WEBMD"

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

    This tool does not provide medical advice. See additional information.

    Other Answers On: