How can antidepressants help treat chronic pain and depression?
The fact that chronic pain and depression may involve the same nerves and neurotransmitters means that antidepressants can improve both chronic pain and depression.
A lot of evidence shows that tricyclic antidepressants can work well for certain kinds of neurologically-based pain (such as pinched nerves or migraine headaches). But, because of side effects, their use is often limited. Doctors prescribe some newer antidepressants to treat painful chronic syndromes. They seem to work well, with fewer side effects.
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