senior man sitting up at night
1 / 11

Sleep Problems

Depression can affect your body as well as your mind. Trouble falling or staying asleep is common in people who are depressed. But some may find that they get too much shut-eye.

Swipe to advance
woman with chest pain
2 / 11

Chest Pain

It can be a sign of heart, lung, or stomach problems, so see your doctor to rule out those causes. Sometimes, though, it's a symptom of depression.

Depression can also raise your risk of heart disease. Plus, people who've had heart attacks are more likely to be depressed.

Swipe to advance
woman sleeping on sofa
3 / 11

Fatigue and Exhaustion

If you feel so tired that you don't have energy for everyday tasks -- even when you sleep or rest a lot -- it may be a sign that you're depressed. Depression and fatigue together tend to make both conditions seem worse.

Swipe to advance
woman with neck pain
4 / 11

Aching Muscles and Joints

When you live with ongoing pain it can raise your risk of depression.

Depression may also lead to pain because the two conditions share chemical messengers in the brain. People who are depressed are three times as likely to get regular pain.

Swipe to advance
woman hanging over sink
5 / 11

Digestive Problems

Our brains and digestive systems are strongly connected, which is why many of us get stomachaches or nausea when we're stressed or worried.

Depression can get you in your gut too -- causing nausea, indigestion, diarrhea, or constipation.

Swipe to advance
woman with headache
6 / 11


One study shows that people with major depression are three times more likely to have migraines, and people with migraines are five times more likely to get depressed.

Swipe to advance
unhappy woman in restaurant
7 / 11

Changes in Appetite or Weight

Some people feel less hungry when they get depressed. Others can't stop eating. The result can be weight gain or loss, along with lack of energy.

Depression has been linked to eating disorders like bulimia, anorexia, or binge eating.

Swipe to advance
woman rubbing aching back
8 / 11

Back Pain

When it hurts you there on a regular basis, it may contribute to depression. And people who are depressed may be four times more likely to get intense, disabling neck or back pain.

Swipe to advance
man standing with arms on head
9 / 11

Agitated and Restless

Sleep problems or other depression symptoms can make you feel this way. Men are more likely than women to be irritable when they're depressed.

Swipe to advance
couple sleeping back to back
10 / 11

Sexual Problems

If you're depressed, you might lose your interest in sex. Some prescription drugs that treat depression can also take away your drive and affect performance. Talk to your doctor about your medicine options.

Swipe to advance
family hula hooping together
11 / 11


Research suggests that if you do it regularly, it releases chemicals in your brain that make you feel good, improve your mood, and reduce your sensitivity to pain.

Although physical activity alone won't cure depression, it can help ease it over the long term.

If you're depressed, it can sometimes be hard to get the energy to exercise. But try to remember that it can ease fatigue and help you sleep better.

Swipe to advance

Up Next

Next Slideshow Title

Sources | Medically Reviewed on 09/11/2019 Reviewed by Smitha Bhandari, MD on September 11, 2019


(1)    Kim Carson / Digital Vision
(2)    Aubrey Humbert / BSIP
(3)    Garry Wade / Taxi
(4)    Bartomeu Amengual / Photolibrary
(5)    Peter Cade / Photographer's Choice
(6)    Christopher Robbins / Digital Vision
(7)    Ian Sanderson / Photographer's Choice
(8)    Bartomeu Amengual / AGE Fotostock
(9)    J.A. Bracchi / OJO Images
(10)    Peter Cade / Iconica
(11)    David Buffington / Blend Images



National Institute of Mental Health: "Depression," "Changes in Appetite."
National Sleep Foundation: "Depression and Sleep."
Eken, C. The Journal of Emergency Medicine, 2010.
Cleveland Clinic Journal of Medicine: "Heart disease and depression: Don't Ignore the relationship."
Skapinakis, P. Psychosomatic Medicine, May/June 2004.
PubMed Health: "Major Depression."
UC Berkeley University Health Services: "Clinical Depression."
Harvard Health Publications: "Depression and pain," "Depression and pain," "Exercise and Depression."
Trivedi, M. Primary Care Companion to the Journal of Clinical Psychiatry, 2004.
Anxiety Disorders Association of America: "Irritable Bowel Syndrome (IBS)."
Lydiard, R. Journal of Clinical Psychology, 2001.
Stanford School of Medicine: "Digestive problems early in life may increase risk for depression, study suggests"
National Headache Foundation: "Depression and Headache," "Depression Linked to Daily Head Pain."
University of California, Berkeley, Health Services: "Tension Headache Fact Sheet."
National Mental Health Association: "Eating Disorders and Depression."
Mental Health America: "Depression in Women."
Science Daily: "Depression Can Lead to Back Pain."
American Family Physician: "Depression and sexual desire."
Cleveland Clinic: "Sexual Problems and Depression."
American Psychological Association: "Exercise Helps Keep Your Psyche Fit."

Reviewed by Smitha Bhandari, MD on September 11, 2019

This tool does not provide medical advice. See additional information.

THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.