Normally when you eat, your blood sugar rises. Your pancreas, a long gland deep in the belly, releases a hormone called insulin. It helps move sugar from your blood into your cells for energy and storage. Then your blood sugar goes back down to normal.
If you have type 2 diabetes, your body uses insulin poorly. Glucose builds up in your blood. This excess sugar can damage blood vessels around your body. Diabetes can lead to heart disease, nerve damage, eye disease, and kidney damage.
When Do I Need the Test?
You might need an oral glucose tolerance test if you:
- Are overweight or obese
- Have a close family member with diabetes
- Have high blood pressure
- Have high triglycerides (a type of fat in your blood)
- Have polycystic ovarian syndrome (which causes menstrual problems)
- Delivered a baby who weighed more than 9 pounds
- Had gestational diabetes during a past pregnancy
A shorter version of this test is done between the 24th and 28th week of pregnancy to see whether you have gestational diabetes. It's called the oral glucose challenge test.
How Do I Get Ready?
To get an accurate result on the OGTT, eat about 150 grams of carbohydrates each day for 3 days before the test. Don't eat or drink anything except water after about 10 o’clock the night before.
You don't need to do any special prep before the pregnancy glucose challenge test. You can eat in the morning. Just avoid foods with a lot of sugar, such as doughnuts or orange juice.
How Is It Done?
You'll get the OGTT at your doctor's office, a clinic, hospital, or lab. Here’s what happens:
- A nurse or doctor will take a blood sample from a vein in your arm to test your starting blood sugar level.
- You'll then drink a mixture of glucose dissolved in water.
- You'll get another blood glucose test 2 hours later.
During pregnancy, the test is shorter. You'll drink a sweet liquid. Then you'll have a blood test about 60 minutes later.
Any Problems from Taking It?
The OGTT has very few issues. Some people have minor side effects from the sugary drink or from the needle stick.
Side effects from the drink include:
Possible problems from the blood test include:
- Excess bleeding
- More than one attempt to find a vein, which can hurt a little
What Do the Results Mean?
Your blood glucose level should rise after you finish the sugary drink. Then it should go back to normal, as insulin moves glucose into your cells. If your blood sugar takes a long time to go back to normal, you could have diabetes.
You might see a measurement from the test written out as “mg/dL.” It stands for milligrams per deciliter. Two hours after you finish the glucose drink, this is what your results mean:
Below 140 mg/dL: normal blood sugar
Between 140 and 199: impaired glucose tolerance, or prediabetes
200 or higher: diabetes
When you're pregnant, a blood glucose level of 140 mg/dL or higher is abnormal. Your doctor will recommend that you take a 3-hour OGTT. During this longer test, you'll have blood drawn before you drink a sugary solution. Then you'll have your blood tested every hour for three hours.