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How does caffeine affect insulin sensitivity?

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Caffeine may lower your insulin sensitivity. That means your cells don’t react to the hormone by as much as they once did. They don’t absorb as much sugar from your blood after you eat or drink. This causes your body to make more insulin, so you have higher levels after meals. If you have type 2 diabetes, your body already doesn’t use insulin well. After meals, your blood sugar rises higher than normal. Caffeine may make it tougher to bring it down to a healthy point. This may lead to too-high blood sugar levels. Over time, this may raise your chance of diabetes complications, like nerve damage or heart disease.

SOURCES:

FDA: “Medicines in My Home: Caffeine and Your Body.”

Diabetes Care : “Acute Effects of Decaffeinated Coffee and the Major Coffee Components Chlorogenic Acid and Trigonelline on Glucose Tolerance,” “Caffeine: A Cause of Insulin Resistance?” “Caffeine Can Decrease Insulin Sensitivity in Humans,” “Caffeine Increases Ambulatory Glucose and Postprandial Responses in Coffee Drinkers With Type 2 Diabetes,” “Coffee, Caffeine, and Type 2 Diabetes.”

Mayo Clinic: “Caffeine Content for Coffee, Tea, Soda and More,” “Caffeine: Does It Affect Blood Sugar?” “Diabetes: Complications,” “Nutrition and Healthy Eating.”

Joslin Diabetes Center: “What Is Insulin Resistance?”

American Diabetes Association: “Type 2.”

Sacha Uelmen, director of nutrition, American Diabetes Association.

Journal of Clinical Investigation : “Epinephrine-induced Insulin Resistance in Man.”

Nature Review Endocrinology : “Adenosine signalling in diabetes mellitus -- pathophysiology and therapeutic considerations.”

Annals of Internal Medicine : “Impaired Insulin Signaling in Human Adipocytes After Experimental Sleep Restriction: A Randomized, Crossover Study.”

European Journal of Clinical Nutrition : “The Evaluation of Inflammatory and Oxidative Stress Biomarkers on Coffee -- Diabetes Association: Results From the 10-year Follow-up of The ATTICA Study (2002–2012).”

Reviewed by Michael Dansinger on April 13, 2017

SOURCES:

FDA: “Medicines in My Home: Caffeine and Your Body.”

Diabetes Care : “Acute Effects of Decaffeinated Coffee and the Major Coffee Components Chlorogenic Acid and Trigonelline on Glucose Tolerance,” “Caffeine: A Cause of Insulin Resistance?” “Caffeine Can Decrease Insulin Sensitivity in Humans,” “Caffeine Increases Ambulatory Glucose and Postprandial Responses in Coffee Drinkers With Type 2 Diabetes,” “Coffee, Caffeine, and Type 2 Diabetes.”

Mayo Clinic: “Caffeine Content for Coffee, Tea, Soda and More,” “Caffeine: Does It Affect Blood Sugar?” “Diabetes: Complications,” “Nutrition and Healthy Eating.”

Joslin Diabetes Center: “What Is Insulin Resistance?”

American Diabetes Association: “Type 2.”

Sacha Uelmen, director of nutrition, American Diabetes Association.

Journal of Clinical Investigation : “Epinephrine-induced Insulin Resistance in Man.”

Nature Review Endocrinology : “Adenosine signalling in diabetes mellitus -- pathophysiology and therapeutic considerations.”

Annals of Internal Medicine : “Impaired Insulin Signaling in Human Adipocytes After Experimental Sleep Restriction: A Randomized, Crossover Study.”

European Journal of Clinical Nutrition : “The Evaluation of Inflammatory and Oxidative Stress Biomarkers on Coffee -- Diabetes Association: Results From the 10-year Follow-up of The ATTICA Study (2002–2012).”

Reviewed by Michael Dansinger on April 13, 2017

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Why does caffeine affect insulin and blood sugar levels?

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