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What causes nephrogenic diabetes insipidus?

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Diabetes insipidus is caused by problems related to a hormone called antidiuretic hormone or ADH. ADH is produced in a part of the brain called the hypothalamus. It's stored in the pituitary gland. Release of ADH is triggered by fluid loss or dehydration. When it's released, it causes the kidneys to retain water. This results in a decrease and concentration of urine.

From: Nephrogenic Diabetes Insipidus WebMD Medical Reference

SOURCES:

Fujiwara, T. 2005; vol 16: pp 2836-2846. Journal of the American Society of Nephrology,

Boton, R. 1987; vol 10: pp 329-345. American Journal of Kidney Disease,

Rose, B. 5th edition, McGraw Hill, 2001. Clinical Physiology of Acid-Base and Electrolyte Disorders,

Garofeanu, C. 2005; vol 45: pp 626-637. American Journal of Kidney Disease,

MedlinePlus: "Diabetes Insipidus."

Libber, S. 1986; vol 108: pp 305-311. Journal of Pediatrics,

Monnens, L. 1984; vol 66: pp 709-715. Clinical Science,

Streitz J, Jr. 1988; vol 139: pp 784-785. Journal of Urology,

Reviewed by Michael Dansinger on December 25, 2018

SOURCES:

Fujiwara, T. 2005; vol 16: pp 2836-2846. Journal of the American Society of Nephrology,

Boton, R. 1987; vol 10: pp 329-345. American Journal of Kidney Disease,

Rose, B. 5th edition, McGraw Hill, 2001. Clinical Physiology of Acid-Base and Electrolyte Disorders,

Garofeanu, C. 2005; vol 45: pp 626-637. American Journal of Kidney Disease,

MedlinePlus: "Diabetes Insipidus."

Libber, S. 1986; vol 108: pp 305-311. Journal of Pediatrics,

Monnens, L. 1984; vol 66: pp 709-715. Clinical Science,

Streitz J, Jr. 1988; vol 139: pp 784-785. Journal of Urology,

Reviewed by Michael Dansinger on December 25, 2018

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How are my kidneys involved in my nephrogenic diabetes insipidus?

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