Your body takes water from all over to get rid of extra blood sugar. That may cause dry, itchy, cracked, skin, especially on your legs, elbows, feet, and hands. In time, high glucose levels also can damage nerves. This is called diabetic neuropathy. It can make it harder for you to feel cuts, wounds, or infections. Without treatment, they can become bigger problems, like the loss of a toe, foot, or part of your leg.