Health Benefits of Magnesium Glycinate

Magnesium is a mineral that’s important to the health of the brain, heart, and skeletal muscles. Magnesium glycinate is the magnesium salt of glycine, an amino acid, and is the supplement most often taken to increase magnesium levels in the body.

In the U.S., as much as half of the population gets less than the recommended amount of magnesium daily. Magnesium deficiency is associated with type 2 diabetes, metabolic syndrome, high blood pressure, migraines, asthma, depression, and some cancers.

Unhealthy changes in dietary habits, modern food processing methods, and nutrient composition in the soil contribute to this widespread deficiency. Fortunately, there are many ways to adjust your diet to include ingredients naturally rich in magnesium. 

To add more magnesium to your meals, consider these foods:

  • Bananas
  • Black beans
  • Broccoli
  • Brown rice
  • Green Vegetables
  • Nuts
  • Seeds
  • Soybeans
  • Sweet corn
  • Whole grains

As magnesium consumption decreases for some people, calcium supplementation may increase. The resulting imbalance between these two minerals may contribute to the negative effects of magnesium deficiency.

Health Benefits

Magnesium is crucial to cellular function. Magnesium supplements have proven to have several benefits, including the following:

Decreased Severity of Asthma Attacks

Because magnesium helps muscles to relax, it may lessen asthmatic spasms. A survey of clinical studies suggests that this benefit appears to be more available to children than to adults.

Mental Health Regulation

Magnesium plays a key role in brain biochemistry. A deficiency can produce a range of neuromuscular and psychiatric symptoms, including depression.

The first successful study involving the use of magnesium supplements in the treatment of depression was published almost 100 years ago, and numerous studies have since validated both the safety and the effectiveness of the treatment.

Magnesium deficiency may also contribute to other psychological symptoms, including:

However, more research is needed to both confirm the correlations and study how magnesium supplementation may ease these symptoms.

Chronic Fatigue Syndrome (CFS) Treatment

While there is only a limited amount of clinical data available, one study’s results showed that magnesium was one of the only supplements that proved effective in treating CFS.


Chronic Pain Relief

Magnesium appears to help with pain management. In one case study, the condition of a child with debilitating chronic back pain improved rapidly when magnesium glycinate was administered. Their flexibility and general quality of life also improved.

Decreased Frequency and Severity of Migraines

The effectiveness of magnesium supplements in helping people deal with migraines is still questionable. However, there is enough evidence of success that doctors often recommend them as a second-line drug for the condition when primary and traditional treatments fall short.

Reduced Risk of Stroke , Heart Failure , and Diabetes

A review of multiple clinical studies found that increased magnesium levels contributed to a decrease in incidences of strokes, heart disease risk, and chances of developing type 2 diabetes.

Health Risks

Because the kidneys excrete excess amounts of magnesium, it is unusual for a person to suffer from too much magnesium. Magnesium glycinate is considered safe for most people.

As with any supplements, you should consult with your doctor before taking magnesium glycinate, particularly if you are on maintenance medication or have a kidney or heart condition. 

Buy your supplements only from trusted brands and sources.

Amounts and Dosage

The recommended daily allowance of magnesium glycinate varies by age, gender, and condition. Look at supplement labels to see how much magnesium is present, and check with your doctor to make sure that any given dosage is appropriate for you. 

WebMD Medical Reference Reviewed by Dan Brennan, MD on November 06, 2020



BMC Complementary and Alternative Medicine: “Complementary and Alternative Medicine for Patients with Chronic Fatigue Syndrome.”

BMC Medicine: “Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies.”

Journal of Pain Relief: “Rapid Resolution of Chronic Back Pain with Magnesium Glycinate in a Pediatric Patient.”

Nutrients: “Magnesium: Are We Consuming Enough?”

Nutrition Reviews: “Suboptimal magnesium status in the United States: Are the health consequences underestimated?”

Pharmacological Reports: “Magnesium in Depression.”

Physiological Reviews: “Magnesium in Man: Implications for Health and Disease.”

The Clinical Biochemist Reviews: “Magnesium Metabolism and its Disorders.”

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