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What are risks of using SAM-e?

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If you have any medical issues, check with a doctor before you start using SAM-e supplements. SAM-e might not be safe for people with conditions such as bipolar disorder, Parkinson's disease, and diabetes. Because SAM-e can affect the blood vessels, stop using SAM-e two weeks before getting surgery.

From: SAM-e (S-adenosylmethionine, SAMe) WebMD Medical Reference

SOURCES:

Fundukian, L., ed. , third edition, 2009. The Gale Encyclopedia of Alternative Medicine

Memorial Sloan-Kettering Cancer Center web site: “About Herbs: SAM-e.”

Agency for Healthcare Research and Quality web site: "S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease."

Natural Medicines Comprehensive Database web site: “SAMe.”

Natural Standard Patient Monograph: “SAMe.”

Reviewed by Melinda Ratini on March 26, 2019

SOURCES:

Fundukian, L., ed. , third edition, 2009. The Gale Encyclopedia of Alternative Medicine

Memorial Sloan-Kettering Cancer Center web site: “About Herbs: SAM-e.”

Agency for Healthcare Research and Quality web site: "S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease."

Natural Medicines Comprehensive Database web site: “SAMe.”

Natural Standard Patient Monograph: “SAMe.”

Reviewed by Melinda Ratini on March 26, 2019

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What are interactions of SAM-e?

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