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Who shouldn't take SAM-e?

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Given the lack of evidence about safety, SAM-e is not recommended for children or for women who are breastfeeding. Although SAM-e has been studied as a treatment for liver problems during pregnancy, pregnant women should only use SAM-e if a doctor recommends it.

From: SAM-e (S-adenosylmethionine, SAMe) WebMD Medical Reference

SOURCES:

Fundukian, L., ed. , third edition, 2009. The Gale Encyclopedia of Alternative Medicine

Memorial Sloan-Kettering Cancer Center web site: “About Herbs: SAM-e.”

Agency for Healthcare Research and Quality web site: "S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease."

Natural Medicines Comprehensive Database web site: “SAMe.”

Natural Standard Patient Monograph: “SAMe.”

Reviewed by Melinda Ratini on March 26, 2019

SOURCES:

Fundukian, L., ed. , third edition, 2009. The Gale Encyclopedia of Alternative Medicine

Memorial Sloan-Kettering Cancer Center web site: “About Herbs: SAM-e.”

Agency for Healthcare Research and Quality web site: "S-Adenosyl-L-Methionine for Treatment of Depression, Osteoarthritis, and Liver Disease."

Natural Medicines Comprehensive Database web site: “SAMe.”

Natural Standard Patient Monograph: “SAMe.”

Reviewed by Melinda Ratini on March 26, 2019

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