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What is Zollinger-Ellison syndrome (ZES)?

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Zollinger-Ellison syndrome (ZES) is a disease of the digestive system. People who have ZES develop tumors known as gastrinomas in the pancreas and small intestine. These tumors make the hormone gastrin. Because gastrin makes stomach acid, 90% of people with ZES get ulcers.

From: What Is Zollinger-Ellison Syndrome? WebMD Medical Reference

SOURCES: 

National Digestive Diseases Information Clearinghouse.

National Institutes of Health. 

Harrison's Principles of Internal Medicine-13th Edition (1994). 

Feldman: Sleisenger and Fordtran's Gastrointestinal and Liver Disease-7th Edition (2002).

Medscape: "Gastrinoma."

Reviewed by Minesh Khatri on October 25, 2017

SOURCES: 

National Digestive Diseases Information Clearinghouse.

National Institutes of Health. 

Harrison's Principles of Internal Medicine-13th Edition (1994). 

Feldman: Sleisenger and Fordtran's Gastrointestinal and Liver Disease-7th Edition (2002).

Medscape: "Gastrinoma."

Reviewed by Minesh Khatri on October 25, 2017

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Are Zollinger-Ellison syndrome (ZES) tumors cancerous?

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THIS TOOL DOES NOT PROVIDE MEDICAL ADVICE. It is intended for general informational purposes only and does not address individual circumstances. It is not a substitute for professional medical advice, diagnosis or treatment and should not be relied on to make decisions about your health. Never ignore professional medical advice in seeking treatment because of something you have read on the WebMD Site. If you think you may have a medical emergency, immediately call your doctor or dial 911.

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