Medicines are used to:
- Treat peptic ulcers by reducing the amount of acid produced by the stomach.
- Kill Helicobacter pyloriHelicobacter pylori (H. pylori) bacteria if they are infecting the stomach lining.
- Protect the lining of the stomach and upper small intestine from injury caused by nonsteroidal anti-inflammatory drugs (NSAIDs). These include aspirin, ibuprofen (such as Advil), and naproxen (such as Aleve).
Medicines to reduce stomach acid
Medicines that reduce the amount of acid produced by the stomach are used to treat all forms of peptic ulcer disease.
- Antacids (such as Tums)
- Acid reducers
Medicines to kill H. pylori bacteria
Medicines to protect the stomach
Acid reducers. These include:
- H2 blockers (such as Zantac).
- Proton pump inhibitors (PPIs) (such as Prilosec).
- Prostaglandin analogs (such as Cytotec).
You can get some H2 blockers and PPIs without a prescription (over the counter or OTC). If you are using OTC acid reducers (such as Prilosec or Pepcid) to help with your symptoms for more than 10 to 14 days at a time, or if your symptoms are very bad, be sure to see your doctor.