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Can allergy medications (antihistamines) make you tired?

ANSWER

Some of the most common drugs that can make you tired are:

Allergy medications (antihistamines), such as diphenhydramine, brompheniramine (Bromfed, Dimetapp), hydroxyzine (Vistaril, Atarax), and meclizine (Antivert). Some of these antihistamines are in sleeping pills, too.

From: What Medicines Can Make You Tired? WebMD Medical Reference

SOURCES:

National Sleep Foundation: “Sleepiness, Medication & Drugs: Why Your OTC Medications and Prescription Drugs Might Make You Tired.”

National Institute of Mental Health: “Brain Basics.”

FDA: “Caution: Some Over-the-Counter Medicines May Affect Your Driving.”

National Capital Poison Center: “Antihistamines: Using Them Safely.”

Mayo Clinic: “Tricyclic Antidepressants and Tetracyclic Antidepressants.”

County of San Mateo Health System: “Benzodiazepines.”

American Heart Association: “Types of Blood Pressure Medications.”

American Cancer Society: “What Causes Cancer-related Fatigue?”

Spine-health: “Muscle Relaxants.”

Cedars-Sinai: “Muscle Relaxants for Orthopedic Conditions.”

Breastcancer.org: “Narcotic Analgesics (Opioids).”

Epilepsy Foundation: “How Medicines Work.”

Cleveland Clinic: “Epilepsy Medications.”

Kaiser Permanente: “How to Prevent Tiredness or Fatigue Caused by Your Medicines.”

Reviewed by William Blahd on August 24, 2017

SOURCES:

National Sleep Foundation: “Sleepiness, Medication & Drugs: Why Your OTC Medications and Prescription Drugs Might Make You Tired.”

National Institute of Mental Health: “Brain Basics.”

FDA: “Caution: Some Over-the-Counter Medicines May Affect Your Driving.”

National Capital Poison Center: “Antihistamines: Using Them Safely.”

Mayo Clinic: “Tricyclic Antidepressants and Tetracyclic Antidepressants.”

County of San Mateo Health System: “Benzodiazepines.”

American Heart Association: “Types of Blood Pressure Medications.”

American Cancer Society: “What Causes Cancer-related Fatigue?”

Spine-health: “Muscle Relaxants.”

Cedars-Sinai: “Muscle Relaxants for Orthopedic Conditions.”

Breastcancer.org: “Narcotic Analgesics (Opioids).”

Epilepsy Foundation: “How Medicines Work.”

Cleveland Clinic: “Epilepsy Medications.”

Kaiser Permanente: “How to Prevent Tiredness or Fatigue Caused by Your Medicines.”

Reviewed by William Blahd on August 24, 2017

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Can antidepressants make you tired?

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