Who should not take Tacrolimus?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • severe infection
  • malignant tumor or cancer
  • diabetes
  • low amount of magnesium in the blood
  • low amount of calcium in the blood
  • high amount of potassium in the blood
  • low amount of potassium in the blood
  • disorder of nerve
  • high blood pressure
  • very rapid heartbeat - torsades de pointes
  • slow heartbeat
  • prolonged QT interval on EKG
  • chronic heart failure
  • abnormal EKG with QT changes from birth
  • severe liver disease
  • kidney damage
  • Coma
  • delirium
  • Disorder of Lymphoid Tissue After Transplant
  • pregnancy
  • Malignant Lymphoma
  • a rupture in the wall of the stomach or intestine
  • Progressive Disease in the White Matter of the Brain
  • Brain-Capillary Leak Syndrome
  • BK Virus Reactivation causing Kidney Problems
  • pure red cell aplasia


  • Macrolide Immunosuppressant

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.