Who should not take Oxycodone HCL?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • systemic mastocytosis
  • untreated decreased level of thyroid hormones
  • alcohol intoxication
  • drug abuse
  • cor pulmonale
  • low blood pressure
  • asthma attack
  • decreased lung function
  • paralysis of the intestines
  • blockage of the stomach or intestine
  • constipation
  • liver problems
  • biliary and gallbladder problem
  • acute inflammation of the pancreas
  • coma
  • seizures
  • a condition where the body is unable to maintain adequate blood flow called shock
  • an inability to completely empty the bladder
  • weakened patient
  • weakness and wasting of the body
  • high pressure within the skull
  • moderate to severe kidney impairment
  • inherited dysfunction of autonomic nerve function
  • worsening chronic obstructive pulmonary disease
  • history of opioid overdose
  • a brain tumor
  • a condition where the adrenal glands produce less hormones called Addison's disease
  • dehydration
  • psychosis caused by sudden alcohol withdrawal
  • toxic psychosis
  • mood changes
  • suicidal thoughts
  • cor pulmonale
  • slow heartbeat
  • abnormal heart rhythm
  • emphysema
  • asthma attack
  • stomach or intestinal tract operation
  • ulcerative colitis, an inflammatory condition of the intestines
  • inflammatory bowel disease
  • liver problems
  • disease of the gallbladder
  • spasm of a bile duct tract
  • decreased kidney function
  • narrowing of the tube that empties urine from the bladder
  • enlarged prostate
  • seizures
  • sleep apnea
  • an inability to completely empty the bladder
  • weakened patient
  • intense abdominal pain
  • morbid obesity

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.