Who should not take Rheumatrex?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • severe infection
  • extreme loss of body water
  • condition resulting from a defective immune system
  • decreased function of bone marrow
  • low blood counts due to bone marrow failure
  • severe anemia
  • severely decreased platelets
  • decreased white blood cells
  • alcoholism
  • escape of fluid into the lungs
  • interstitial pneumonitis
  • lung fibrosis
  • canker sore
  • ulcer from stomach acid
  • ulcerated colon
  • hardening of the liver caused by alcohol
  • hardening of the liver
  • excess liver fibrous tissue
  • severe liver disease
  • kidney disease with reduction in kidney function
  • diarrhea
  • ascites
  • abnormal liver function tests
  • pregnancy
  • a mother who is producing milk and breastfeeding


  • Folic Acid Antagonist
  • Methotrexate Analogues

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.