Who should not take Nortriptyline HCL?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • overactive thyroid gland
  • Schizophrenia
  • Manic-Depression
  • having thoughts of suicide
  • alcoholism
  • serotonin syndrome - adverse drug interaction
  • lower seizure threshold
  • closed angle glaucoma
  • heart attack within the last 30 days
  • sinus tachycardia
  • prolonged QT interval on EKG
  • abnormal heart rhythm
  • abnormal EKG with QT changes from birth
  • stroke
  • severe liver disease
  • kidney failure
  • enlarged prostate
  • seizures
  • cannot empty bladder
  • CYP2D6 poor metabolizer
  • risk of angle-closure glaucoma due to narrow angle of anterior chamber of eye


  • Tricyclic Compounds

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.