Asunaprevir/Gemfibrozil Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Gemfibrozil may increase how quickly your body processes your asunaprevir.

What might happen:

The amount of asunaprevir in your blood may decrease, and it may not work as well.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change one of your medicines to make sure your asunaprevir is effective.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Sunvepra (asunaprevir) Australia Prescribing Information. Bristol-Myers Squibb Australia Pty Ltd April 5, 2019.
  • 2.This information is based on or an extract from the UW Metabolism and Transport Drug Interaction Database (DIDB) Platform, Copyright University of Washington 1999-2019..
  • 3.Eley T, He B, Huang SP, Stonier M, Bedford W, Kandoussi H, Gardiner DF, Sims K, Li W, Bertz RJ. Effect of multiple-dose ketoconazole and the effect of multiple-dose rifampin on pharmacokinetics (PK) of the HCV NS3 protease inhibitor asunaprevir. Presented at the 8th International Workshop on Clinical Pharmacology of Hepatitis Therapy. Cambridge, MA. June 26-27, 2013.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.