Protriptyline HCL Side Effects by Likelihood and Severity

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Abnormal Heart Rhythm
  • Abnormal Sexual Function

If experienced, these tend to have a Less Severe expression

  • Heartburn

RARE side effects


If experienced, these tend to have a Severe expression

  • A Disorder With Excess Antidiuretic Hormone Called Syndrome Of Inappropriate Antidiuretic Hormone
  • A Form Of Mania That Has A Lower Severity Of Symptoms
  • A Heart Attack
  • A Skin Rash
  • A Stroke
  • A Type Of Slowed Heart Rhythm Disorder Called Heart Block
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Liver Function Tests
  • Abnormal Results For A Test Recording The Brain's Activity
  • An Inability To Completely Empty The Bladder
  • Blurred Vision
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Confusion
  • Decreased Blood Platelets
  • Decreased Function Of Bone Marrow
  • Disturbance In The Ability Of The Eye To Focus
  • Enlarged Breasts
  • Extrapyramidal Disease, A Type Of Movement Disorder
  • Hair Loss
  • Hallucinations
  • Increased Eosinophils In The Blood
  • Increased Pressure In The Eye
  • Increased Sensitivity Of The Skin To The Sun
  • Itching
  • Large Purple Or Brown Skin Blotches
  • Low Blood Pressure
  • Low Levels Of White Blood Cells
  • Muscle Tremors
  • Nervousness
  • Orthostatic Hypotension, A Form Of Low Blood Pressure
  • Panic Disorder
  • Paralysis Of The Intestines
  • Prolonged QT Interval On EKG
  • Ringing In The Ears
  • Secondary Angle-Closure Glaucoma, A Type Of Eye Disorder
  • Seizures
  • Suicidal Thoughts
  • Swelling Of The Testicles
  • The Inability To Have An Erection
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell

If experienced, these tend to have a Less Severe expression

  • A Discolored Tongue
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • Agitation
  • Altered Interest In Having Sexual Intercourse
  • An Increased Need To Urinate Often
  • Anxious Feelings
  • Constipation
  • Decreased Appetite
  • Delusions
  • Diarrhea
  • Difficulty Sleeping
  • Dilated Pupils
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Excessive Sweating
  • Fast Heartbeat
  • Fever
  • Generalized Weakness
  • Head Pain
  • Heart Throbbing Or Pounding
  • High Blood Pressure
  • High Blood Sugar
  • Hives
  • Inflammation Of The Parotid Gland
  • Loss Of Muscle Coordination
  • Low Blood Sugar
  • Low Energy
  • Nausea
  • Nightmares
  • Numbness And Tingling
  • Puffy Face From Water Retention
  • Small Reddish-Purplish Pin-Point Sized Spots On Skin
  • Stomach Cramps
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Taste Impairment
  • Temporary Redness Of Face And Neck
  • Urination During The Night
  • Visible Water Retention
  • Vomiting
  • Weight Gain
  • Weight Loss

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.