Does ITRACONAZOLE Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • MISC ANTIFUNGAL AGENTS/ASTEMIZOLE; TERFENADINE
  • ITRACONAZOLE/SELECTED HMG-COA REDUCTASE INHIBITORS
  • ITRACONAZOL;KETOCONAZOL;LEVOKETOCONAZ/SLT BENZODIAZEPINES
  • ITRACONAZOLE; KETOCONAZOLE; LEVOKETOCONAZOLE/ISONIAZID
  • STRONG CYP3A4 INHIBITORS/PIMAVANSERIN (> 10 MG)
  • STRONG CYP3A4 INHIBITORS/MAVACAMTEN
  • STRONG CYP3A4 INHIBITORS/PACRITINIB
  • SELECTED STRONG CYP3A4 INHIBITORS/CONIVAPTAN
  • SELECTED STRONG CYP3A4 INHIBITORS/ALFUZOSIN
  • STRONG CYP3A4 INHIBITORS/FINERENONE
  • STRONG CYP3A4 INHIBITORS/VOCLOSPORIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LONAFARNIB
  • STRONG CYP3A4 INHIBITORS/LUMATEPERONE (>10.5 MG)
  • STRONG CYP3A4 INHIBITORS/UBROGEPANT
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR;DARUNAVIR/LERCANIDIPINE
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (>50MG)
  • STRONG CYP3A4 INHIBITORS/DAPAGLIFLOZIN-SAXAGLIPTIN-METFORMIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • SELECTED STRONG CYP3A4 INHIBITORS/ISAVUCONAZONIUM
  • STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (> 10 MG)
  • STRONG CYP3A4 INHIBITORS/NALOXEGOL
  • STRONG CYP3A4 INHIBITORS/AVANAFIL
  • 3A4INHIB/DAPOXETINE;LEVOMILNACIPRAN(>80MG);VILAZODONE(>20MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • STRONG CYP3A4 INHIBITORS/SLT HIGH STRENGTH ANTIMUSCARINICS
  • SELECTED STRONG CYP3A4 INHIBITORS/DOMPERIDONE; CISAPRIDE
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/TICAGRELOR
  • SELECTED AZOLE ANTIFUNGAL AGENTS/LURASIDONE
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/SAXAGLIPTIN (>2.5 MG)
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR/DRONEDARONE
  • ITRACONAZOL;KETOCONAZOL;LEVOKETOCON/FELODIPINE;NISOLDIPINE
  • P-GP AND STRONG CYP3A4 INHIBITORS/RIVAROXABAN
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/RANOLAZINE
  • STRONG CYP3A4 INHIBITORS/TOLVAPTAN
  • STRONG CYP3A4 INHIBITORS; PROTEASE INHIBITORS/IVABRADINE
  • STRONG CYP3A4 INHIBITORS/SILODOSIN; TAMSULOSIN
  • ITRACONAZOLE;KETOCONAZO/LEVOMETHADONE;LEVOMETHADYL;METHADONE
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (> 5 MG)
  • ITRACONAZOLE; KETOCONAZOLE/ERGOT ALKALOIDS
  • STRONG CYP3A4 INHIBITORS/EPLERENONE
  • STRONG CYP3A4 INHIBITORS/IRINOTECAN
  • SELECTED AZOLE ANTIFUNGALS/ELETRIPTAN
  • ITRACONAZOLE; KETOCONAZOLE(ORAL)/DOFETILIDE
  • SELECTED AZOLE ANTIFUNGALS/DISOPYRAMIDE; QUINIDINE
  • SELECTED AZOLE ANTIFUNGALS/PIMOZIDE
  • ITRACONAZOLE; KETOCONAZOLE/SERTINDOLE
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • ITRACONAZOLE; KETOCONAZOLE/DIGOXIN
  • SELECT AZOLE ANTIFUNGAL AGENTS/COUMARIN ANTICOAGULANTS
  • AZOLE ANTIFUNGAL AGENTS/SELECTED RIFAMYCINS
  • ITRACONAZOLE; KETOCONAZOLE/NEVIRAPINE
  • ITRACONAZOLE; KETOCONAZOLE; POSACONAZOLE/EFAVIRENZ
  • AZOLE ANTIFUNGAL AGENTS/RIFABUTIN
  • SELECTED AZOLE ANTIFUNGAL AGENTS/TACROLIMUS
  • STRONG CYP3A4 INHIBITORS/MITAPIVAT
  • STRONG CYP3A4 INHIBITOR/TOLTERODINE (>1 MG IR OR >2 MG ER)
  • STRONG CYP3A4 INHIBITORS/RIVOCERANIB
  • STRONG CYP3A4 INHIBITORS/DARIDOREXANT
  • STRONG CYP3A4 INHIBITORS/LEVOKETOCONAZOLE
  • STRONG CYP3A4 INHIBITORS/UPADACITINIB (>=30 MG)
  • STRONG CYP3A4 INHIBITORS/RUPATADINE
  • HYDROXYPROPYL BETADEX (ITRACONAZOLE SOLUTION)/ASCIMINIB
  • STRONG CYP3A4 INHIBITORS/SURUFATINIB
  • STRONG CYP3A4 INHIBITORS/AVACOPAN
  • STRONG CYP3A4 INHIBITORS/MOBOCERTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/FEXINIDAZOLE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • DUAL STRONG CYP3A4 INHIBITOR & P-GP INHIBITORS/TEPOTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • STRONG CYP3A4 INHIBITORS/TOREMIFENE
  • STRONG CYP3A4 INHIBITORS/SUNITINIB
  • STRONG CYP3A4 INHIBITORS/PAZOPANIB
  • STRONG CYP3A4 INHIBITORS/NILOTINIB
  • STRONG CYP3A4 INHIBITORS/LAPATINIB
  • STRONG CYP3A4 INHIBITORS/DASATINIB
  • STRONG CYP3A4 INHIBITORS/CRIZOTINIB
  • STRONG CYP3A4 INHIBITORS/CERITINIB
  • STRONG CYP3A4 INHIBITORS/VINFLUNINE
  • STRONG CYP3A4 INHIBITORS/VINCRISTINE
  • STRONG CYP3A4 INHIBITORS/VINBLASTINE
  • STRONG CYP3A4 INHIBITORS/TOFACITINIB
  • STRONG CYP3A4 INHIBITORS/SONIDEGIB
  • STRONG CYP3A4 INHIBITORS/RUXOLITINIB
  • STRONG CYP3A4 INHIBITORS/PONATINIB
  • STRONG CYP3A4 INHIBITORS/PALBOCICLIB
  • STRONG CYP3A4 INHIBITORS/PACLITAXEL
  • STRONG CYP3A4 INHIBITORS/OLAPARIB
  • STRONG CYP3A4 INHIBITORS/IXABEPILONE
  • STRONG CYP3A4 INHIBITORS/IDELALISIB
  • STRONG CYP3A4 INHIBITORS/ERLOTINIB
  • STRONG CYP3A4 INHIBITORS/DOXORUBICIN
  • STRONG CYP3A4 INHIBITORS/DOCETAXEL
  • STRONG CYP3A4 INHIBITORS/DABRAFENIB
  • STRONG CYP3A4 INHIBITORS/COBIMETINIB
  • STRONG CYP3A4 INHIBITORS/CABOZANTINIB
  • STRONG CYP3A4 INHIBITORS/CABAZITAXEL
  • STRONG CYP3A4 INHIBITORS/AXITINIB
  • STRONG CYP3A4 INHIBITORS/SUVOREXANT
  • STRONG CYP3A4 AND P-GP INHIBITORS/PRALSETINIB
  • STRONG CYP3A4 INHIBITORS/PLITIDEPSIN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • STRONG CYP3A4 INHIBITORS/SELPERCATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • STRONG CYP3A4 INHIBITORS/RIMEGEPANT
  • STRONG CYP3A4 INHIBITORS/NIMODIPINE
  • STRONG CYP3A4 INHIBITORS/TAZEMETOSTAT
  • STRONG CYP3A4 INHIBITORS/AVAPRITINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • STRONG CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • STRONG CYP3A4 INHIBITORS/NALDEMEDINE
  • STRONG CYP3A4 INHIBITORS/ISTRADEFYLLINE
  • SELECTED STRONG CYP3A4 INHIBITORS/ORAL LEFAMULIN
  • STRONG CYP3A4 INHIBITORS/FEDRATINIB
  • STRONG CYP3A4 INHIBITORS/ENTRECTINIB
  • STRONG CYP3A4 INHIBITORS/PEXIDARTINIB
  • STRONG CYP3A4 INHIBITORS/BOSUTINIB
  • SELECTED STRONG CYP3A4 INHIBITORS/CLOPIDOGREL
  • SELECTED CYP3A4 INHIBITORS/ELBASVIR-GRAZOPREVIR
  • STRONG CYP3A4 INHIBITORS/LAROTRECTINIB
  • STRONG CYP3A4 INHIBITORS/GLASDEGIB
  • STRONG CYP3A4 INHIBITORS/LORLATINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TALAZOPARIB
  • STRONG CYP3A4 INHIBITORS/DUVELISIB
  • STRONG CYP3A4 INHIBITORS/ELAGOLIX
  • ITRACONAZOLE; KETOCONAZOLE/IVOSIDENIB
  • STRONG CYP3A4 INHIBITORS/ARIPIPRAZOLE LAUROXIL SUBMICRONIZED
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ENCORAFENIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • STRONG CYP3A4 INHIBITORS/IBRUTINIB
  • STRONG CYP3A4 INHIBITORS/ACALABRUTINIB
  • STRONG CYP3A4 INHIBITORS/ABEMACICLIB
  • STRONG CYP3A4 INHIBITORS/COPANLISIB
  • STRONG CYP3A4 INHIB;MODERATE 3A4 & P-GP DUAL INHIB/NERATINIB
  • STRONG CYP3A4 INHIBITORS/BRIGATINIB
  • STRONG CYP3A4 INHIBITORS/VALBENAZINE
  • STRONG CYP3A4 INHIBITORS/RIBOCICLIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • SLT STRONG 3A4 INHIBITORS/SILDENAFIL(PAH);TADALAFIL(BPH,PAH)
  • STRONG CYP3A4 INHIBITORS/VENETOCLAX
  • STRONG CYP3A4 INHIBITORS/VEMURAFENIB
  • STRONG CYP3A4 INHIBITORS/TRABECTEDIN
  • STRONG CYP3A4 INHIBITORS/CARIPRAZINE
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/BEDAQUILINE;DELAMANID
  • SLT STRONG CYP3A4 INHIBITOR & SUBSTRATE/LUMACAFTOR-IVACAFTOR
  • STRONG CYP3A4 INHIBITORS/TRASTUZUMAB EMTANSINE
  • STRONG 3A4 INHIBITORS/ESZOPICLONE > 2 MG; ZOPICLONE > 5 MG
  • STRONG CYP3A4 INHIBITORS/DACLATASVIR
  • STRONG & MODERATE CYP3A4 INHIBITORS/ELIGLUSTAT
  • STRONG CYP3A4 INHIBITORS/VORAPAXAR
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG CYP3A4 INHIBITORS/MACITENTAN
  • ITRACONAZOLE; KETOCONAZOLE(ORAL); LEVOKETOCONAZOLE/RIOCIGUAT
  • STRONG CYP3A4 INHIBITORS/QUETIAPINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/BOSENTAN
  • P-GP AND STRONG CYP3A4 INHIBITORS/APIXABAN
  • STRONG CYP3A4 INHIBITORS/REGORAFENIB
  • STRONG CYP3A4 INHIBITORS; AMPRENAVIR;ATAZANAVIR/MIFEPRISTONE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/ALISKIREN
  • ITRACONAZOLE; KETOCONAZOLE/SALMETEROL
  • STRONG CYP3A4 INHIBITORS/EVEROLIMUS
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • STRONG CYP3A4 INHIBITORS/MARAVIROC
  • SLT AZOLE ANTIFUNGALS/SELECTED ANTICONVULSANTS; BARBITURATES
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR/COLCHICINE
  • SELECTED CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • ITRACONAZOLE; KETOCONAZOLE/ERYTHROMYCIN; TELITHROMYCIN
  • SELECTED CYP3A4 INHIBITORS/TRAZODONE
  • SLT AZOLE ANTIFUNGAL; LEVOKETOCONAZ/SELECTED VINCA ALKALOIDS
  • SELECTED AZOLE ANTIFUNGAL AGENTS/SELECTED IMMUNOSUPPRESSANTS
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • ITRACONAZOLE; KETOCONAZOLE/AGENTS AFFECTING GASTRIC PH
  • AZOLE ANTIFUNGALS/SULFONYLUREAS
  • ITRACONAZOLE; KETOCONAZOLE/SELECTED CYP3A4 INHIBITORS
  • ORAL ITRACONAZOLE; KETOCONAZOLE/HYOSCYAMINE
  • SELECTED AZOLE ANTIFUNGALS/BOCEPREVIR; TELAPREVIR
  • ITRACONAZOLE/ATORVASTATIN (<=20MG)
  • STRONG CYP3A4 INHIBITORS/LUMATEPERONE (<=10.5 MG)
  • STRONG CYP3A4 INHIBITORS/GILTERITINIB
  • STRONG CYP3A4 INHIBITORS/TOLTERODINE (<=1 MG OR <=2 MG ER)
  • STRONG CYP3A4 INHIBITORS/UPADACITINIB (<30 MG)
  • STRONG CYP3A4 INHIBITORS/ATOGEPANT
  • STRONG CYP3A4 INHIBITORS/IBREXAFUNGERP
  • STRONG CYP3A4 INHIBITORS/REPAGLINIDE
  • STRONG CYP2D6 OR CYP3A4 INHIBITORS/OLICERIDINE
  • STRONG CYP3A4 INHIBITORS/FOSTAMATINIB
  • STRONG CYP3A4 INHIBITORS/OSILODROSTAT
  • SELECTED STRONG CYP3A4 INHIBITORS/ROMIDEPSIN
  • STRONG CYP3A4 INHIBITORS/CANNABIDIOL-TETRAHYDROCANNABINOL
  • SELECTED STRONG CYP3A4 INHIBITORS/MEFLOQUINE
  • STRONG CYP3A4 INHIBITORS/ZANUBRUTINIB
  • P-GP AND STRONG CYP3A4 INHIBITORS/DAROLUTAMIDE
  • SELECTED STRONG CYP3A4 INHIBITORS/ILOPERIDONE
  • STRONG CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • SELECT P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • ITRACONAZOLE/NADOLOL
  • STRONG CYP3A4 INHIBITORS/CLONAZEPAM
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • STRONG CYP3A4 INHIBITORS/MIDOSTAURIN
  • STRONG CYP3A4 INHIBITORS/PIMAVANSERIN (<= 10 MG)
  • SELECTED CYP3A4 INHIBITORS/BROMOCRIPTINE; CABERGOLINE
  • SELECT P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • STRONG 3A4 INHIB/LEVOMILNACIPRAN(<=80MG);VILAZODONE(<=20MG)
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • SELECTED CYP3A4 INHIBITORS/VARDENAFIL (<= 5 MG)
  • ITRACONAZOLE;KETOCONAZOLE/SELECT BENZODIAZEPINES; BUSPIRONE
  • STRONG CYP3A4 INHIBITORS/PANOBINOSTAT (<= 10 MG)
  • STRONG CYP3A4 INHIB;ATAZANAV;DARUNAVIR/SAXAGLIPTIN(<=2.5 MG)
  • SELECTED AZOLE ANTIFUNGALS/SELECTED CALCIUM CHANNEL BLOCKERS
  • SLT AZOLE ANTIFUNGALS; LEVOKETOCONAZOLE/GEFITINIB; IMATINIB
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • SELECTED AZOLE ANTIFUNGAL AGENTS/SELECTED CORTICOSTEROIDS
  • SELECTED AZOLE ANTIFUNGALS; LEVOKETOCONAZOLE/BUSULFAN
  • STRONG CYP3A4 INHIBITORS/ESZOPICLONE; ZOPICLONE; ZOLPIDEM
  • STRONG CYP3A4 INHIBITORS/CINACALCET
  • STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR/ARIPIPRAZOLE
  • SELECTED STRONG CYP3A4 INHIBITORS/ARTEMETHER;LUMEFANTRINE
  • STRONG CYP3A4 INHIBITORS/SLT LOW STRENGTH ANTIMUSCARINICS
  • ITRACONAZOLE; KETOCONAZOLE/INDINAVIR
  • SLT STRONG & MODERATE CYP3A4 INHIBITORS/CILOSTAZOL (<=50MG)
  • SLT STRONG CYP3A4 INHIBITORS/SILDENAFIL (ED); TADALAFIL (ED)
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/ETOPOSIDE
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.