What should I Know Regarding Pregnancy, Nursing and Administering GEMCITABINE HCL to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: General-Grade 3 or 4 thrombocytopenia or neutropenia are more common in the elderly. Plasma clearance in the elderly (age 79) is slower resulting in a drug half life that is nearly twice that in young (age 29) patients. The manufacturer does not have any dosing guidelines in the elderly.
  • Pediatric use

  • Severe Precaution: Efficacy not demonstrated in pediatric trials of refractory leukemia , relapsed ALL or AML. Toxicity profile similar to adults.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.