What should I Know Regarding Pregnancy, Nursing and Administering Donepezil HCL ODT to Children or the Elderly?

If you are PREGNANT

  • Requires a Risk/Benefit Assessment:

If you are NURSING


If you are an adult over 60

  • management or monitoring precaution: General-Recent rare reports of rhabdomyolysis and NMS. Cardiovascular-Cholinesterase inhibitors can have vagotonic effects on the SA & AV nodes resulting in bradycardia or AV block. Urogenital-May cause bladder outflow obstruction in those patients who are predisposed. Gastrointestinal-Use with caution in patients with history of or active PUD or GI bleeding. Dose dependent N/V, diarrhea.

Giving Donepezil HCL ODT to a child under 12

  • management or monitoring precaution: No approved indications for treating children. No safety and efficacy established.

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