What should I Know Regarding Pregnancy, Nursing and Administering Paliperidone ER to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • If you are an adult over 60

  • management or monitoring precaution: Renal-Adjust dose according to renal function. Long-acting formulations are not recommended in renal impairment. Neuro/Psych-Higher risk of tardive dyskinesia. May cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Cardiovascular-May cause orthostatic hypotension. Elderly may be more predisposed to drug induced QT prolongation. Gastrointestinal-May cause or worsen constipation. Genitourinary-Urinary retention risk.
  • Pediatric use

  • Severe Precaution: Risks of somnolence, weight gain, glucose, lipid abnormalities. Unknown long term effects on growth and development. Safety and efficacy not established in children age < 12 years.
  • Severe Precaution: Monitor weight and for glucose, lipid abnormalities. Risks include somnolence, akathisia, tremor, dystonia, anxiety, and tachycardia. Unknown long-term effects on growth and development.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.