Does Tykerb Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SELECTED IMMUNOSUPPRESSANTS/NADOFARAGENE FIRADENOVEC
  • WEAK CYP3A4 INHIBITORS/LEMBOREXANT (> 5 MG)
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (>30 MG)
  • SELECTED IMMUNOSUPPRESSANTS/TALIMOGENE LAHERPAREPVEC
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/EFALIZUMAB; NATALIZUMAB
  • UGT1A1 INHIBITORS/IRINOTECAN
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • SLT ANTINEOPLASTIC SYSTEMIC ENZYME INHIB/ST. JOHN'S WORT
  • SLT ANTINEOPLASTIC SYSTEMIC ENZYME INHIB/STRONG 3A4 INDUCERS
  • SLT ANTINEO SYSTEMIC ENZYME INHIBITORS/FLUCONAZOLE
  • SELECTED ORAL BCRP SUBSTRATES/ORAL TEDIZOLID
  • SELECTED ANTINEOPLASTICS THAT PROLONG QT/SAQUINAVIR
  • SELECTED BCRP SUBSTRATES/DAROLUTAMIDE
  • SELECTED ANTINEOPLASTIC SYSTEMIC ENZYME INHIBITORS/RIFABUTIN
  • SELECTED BCRP SUBSTRATES/CAPMATINIB
  • LAPATINIB/STRONG CYP3A4 INHIBITORS
  • LAPATINIB/STRONG CYP3A4 INHIBITORS THAT PROLONG QT
  • LAPATINIB/LONAFARNIB
  • ANTINEOPLASTIC SYSTEMIC ENZYME INHIBITORS/CARBAMAZEPINE
  • ANTINEOPLASTIC SYST ENZYME INHIB THAT PROLONG QT/APALUTAMIDE
  • SLT ANTINEOPLASTIC SYSTEMIC ENZYME INH/LUMACAFTOR-IVACAFTOR
  • SELECTED BCRP SUBSTRATES/OTESECONAZOLE
  • SELECT UGT INHIBITORS/PEXIDARTINIB (125 MG)
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • UGT INHIBITORS/LORAZEPAM EXTENDED RELEASE
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/CLADRIBINE
  • IMMUNOSUPPRESSIV; IMMUNOMODULATORS THAT PROLONG QT/SIPONIMOD
  • IMMUNOSUPPRESSIVES;IMMUNOMODULATORS THAT PROLONG QT/OZANIMOD
  • IMMUNOSUPPRES;IMMUNOMODULATORS THAT PROLONG QT/FINGOLIMOD
  • IMMUNOSUPPRESSIV;IMMUNOMODULATORS THAT PROLONG QT/PONESIMOD
  • P-GP INHIBITORS/RIMEGEPANT
  • MYELOSUPPRESSIVES; IMMUNOMODULATORS/SODIUM IODIDE I 131
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/FILGOTINIB
  • SELECTED IMMUNOSUPPRESSANTS/LEFLUNOMIDE; TERIFLUNOMIDE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/BARICITINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/INEBILIZUMAB
  • UGT1A1 INHIBITORS/SACITUZUMAB GOVITECAN
  • P-GP OR BCRP INHIBITORS THAT PROLONG QT/PAZOPANIB
  • POSSIBLE QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • P-GP INHIBITORS THAT PROLONG QT/ORAL LEFAMULIN
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/UPADACITINIB
  • SELECT UGT INHIBITORS/PEXIDARTINIB
  • SELECTED ORAL INHIBITORS OF BCRP/TALAZOPARIB
  • WEAK CYP3A4 INHIBITORS/ELIGLUSTAT
  • POSSIBLE QT PROLONGING AGENTS/DOMPERIDONE
  • IMMUNOSUPPRES;IMMUNOMODUL/SELECTED MULTIPLE SCLEROSIS AGENTS
  • STRONG UGT1A1 INHIBITORS/BELINOSTAT
  • POSSIBLE QT PROLONGING AGENTS/ANAGRELIDE
  • WEAK CYP3A4 INHIBITORS/LOMITAPIDE (<=30MG)
  • POSSIBLE QT PROLONGING AGENTS/DRONEDARONE
  • POSSIBLE QT PROLONGING AGENTS/ARTEMETHER-LUMEFANTRINE
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/DABIGATRAN
  • POSSIBLE QT PROLONGING AGENTS/DISOPYRAMIDE
  • POSSIBLE QT PROLONGING AGENTS/CISAPRIDE
  • SELECTED QT PROLONGING AGENTS/ZIPRASIDONE
  • POSSIBLE QT PROLONGING AGENTS/SERTINDOLE
  • POSSIBLE QT PROLONGING AGENTS/DROPERIDOL
  • POSSIBLE QT PROLONGING AGENTS/LEVOMETHADYL
  • POSSIBLE QT PROLONGING AGENTS/SPARFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/HALOFANTRINE
  • POSSIBLE QT PROLONGING AGENTS/PIMOZIDE
  • POSSIBLE QT PROLONGING AGENTS/BEPRIDIL
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • LAPATINIB/QT PROLONGING AGENTS
  • SELECTED BCRP SUBSTRATES/SAFINAMIDE
  • POSSIBLE QT PROLONGING AGENTS/ADAGRASIB
  • QT PROLONGING AGENTS/TUCIDINOSTAT
  • QT PROLONGING AGENTS/SAVOLITINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/SARILUMAB; TOCILIZUMAB
  • QT PROLONGING AGENTS/TRICLABENDAZOLE
  • POSSIBLE QT PROLONGING AGENTS/PACRITINIB
  • QT PROLONGING AGENTS/TOLTERODINE
  • SLT MODERATE AND WEAK CYP3A4 INHIBIT/SIROLIMUS PROTEIN-BOUND
  • SELECTED POSSIBLE QT PROLONGING AGENTS/INTRAVENOUS LEFAMULIN
  • POSSIBLE QT PROLONGING AGENTS/MOBOCERTINIB
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/COVID-19 VACCINES
  • POSSIBLE QT PROLONGING AGENTS/FEXINIDAZOLE
  • QT PROLONGING AGENTS/GALANTAMINE
  • POSSIBLE QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • IMMUNOSUPPRESSIVES; IMMUNOMODULATORS/USTEKINUMAB
  • POSSIBLE QT PROLONGING AGENTS/SELPERCATINIB
  • POSSIBLE QT PROLONGING AGENTS/OXALIPLATIN
  • QT PROLONGING AGENTS/OSILODROSTAT
  • QT PROLONGING AGENTS/AMISULPRIDE
  • WEAK CYP3A4 INHIBITORS/UBROGEPANT
  • WEAK CYP3A4 INHIBITORS/LEMBOREXANT (<= 5 MG)
  • MODERATE & WEAK CYP3A4 INHIBITORS THAT PROLONG QT/TACROLIMUS
  • POSSIBLE QT PROLONGING AGENTS/ENTRECTINIB
  • QT PROLONGING AGENTS/PITOLISANT
  • QT PROLONGING AGENTS/GILTERITINIB
  • POSSIBLE QT PROLONGING AGENTS/GLASDEGIB
  • POSSIBLE QT PROLONGING AGENTS/IVOSIDENIB
  • POSSIBLE QT PROLONGING AGENTS/ENCORAFENIB
  • LAPATINIB; RITONAVIR/EDOXABAN (<= 30 MG)
  • POSSIBLE QT PROLONGING AGENTS/TRAZODONE (< 100 MG)
  • POSSIBLE QT PROLONGING AGENTS/LOFEXIDINE
  • POSSIBLE QT PROLONGING AGENTS/MACIMORELIN
  • POSSIBLE QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • QT PROLONGING AGENTS/EFAVIRENZ
  • POSSIBLE QT PROLONGING AGENTS/HYDROXYZINE
  • POSSIBLE QT PROLONGING AGENTS/PIMAVANSERIN
  • POSSIBLE QT PROLONGING AGENTS/OSIMERTINIB
  • POSSIBLE QT PROLONGING AGENTS/SULPIRIDE
  • POSSIBLE QT PROLONGING AGENTS/ERYTHROMYCIN
  • POSSIBLE QT PROLONGING AGENTS/HYDROQUINIDINE; QUINIDINE
  • LAPATINIB; RITONAVIR/EDOXABAN (> 30 MG)
  • POSSIBLE QT PROLONGING AGENTS/LENVATINIB
  • POSSIBLE QT PROLONGING AGENTS/DELAMANID
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • QT PROLONGING AGENTS/SEVOFLURANE
  • POSSIBLE QT PROLONGING AGENTS/TRAZODONE (>= 100 MG)
  • QT PROLONGING AGENTS/ESCITALOPRAM
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • POSSIBLE QT PROLONGING AGENTS/BEDAQUILINE
  • QT PROLONGING AGENTS/PASIREOTIDE
  • POSSIBLE QT PROLONGING AGENTS/SORAFENIB
  • LAPATINIB/DIGOXIN
  • POSSIBLE QT PROLONGING AGENTS/CRIZOTINIB
  • POSSIBLE QT PROLONGING AGENTS/CITALOPRAM
  • POSSIBLE QT PROLONGING AGENTS/VEMURAFENIB
  • SELECTED QT PROLONGERS/ASTEMIZOLE; TERFENADINE
  • POSSIBLE QT PROLONGING AGENTS/EZOGABINE
  • POSSIBLE QT PROLONGING AGENTS/VANDETANIB
  • POSSIBLE QT PROLONGING AGENTS/GADOFOSVESET
  • POSSIBLE QT PROLONGING AGENTS/ERIBULIN
  • QT PROLONGING AGENTS/CIPROFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/ROMIDEPSIN
  • POSSIBLE QT PROLONGING AGENTS/ILOPERIDONE
  • POSSIBLE QT PROLONGING AGENTS/TELAVANCIN
  • POSSIBLE QT PROLONGING AGENTS/TOREMIFENE
  • POSSIBLE QT PROLONGING AGENTS/QUININE
  • POSSIBLE QT PROLONGING AGENTS/ZUCLOPENTHIXOL
  • POSSIBLE QT PROLONGING AGENTS/NILOTINIB
  • UGT INHIBITORS/LORAZEPAM; MEXAZOLAM
  • POSSIBLE QT PROLONGING AGENTS/PALIPERIDONE
  • QT PROLONGING AGENTS/DASATINIB
  • QT PROLONGING AGENTS/RANOLAZINE
  • POSSIBLE QT PROLONGING AGENTS/IVABRADINE
  • POSSIBLE QT PROLONGING AGENTS/MESORIDAZINE
  • POSSIBLE QT PROLONGING AGENTS/THIORIDAZINE
  • POSSIBLE QT PROLONGING AGENTS/AMIODARONE
  • QT PROLONGING AGENTS/LEVOFLOXACIN
  • QT PROLONGING AGENTS/HALOPERIDOL
  • QT PROLONGING AGENTS/NORFLOXACIN
  • QT PROLONGING AGENTS/GEMIFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/LEVOMETHADONE; METHADONE
  • QT PROLONGING AGENTS/APOMORPHINE
  • POSSIBLE QT PROLONGING AGENTS/PROPAFENONE
  • QT PROLONGING AGENTS/DOLASETRON
  • POSSIBLE QT PROLONGING AGENTS/SOTALOL
  • POSSIBLE QT PROLONGING AGENTS/MOXIFLOXACIN
  • QT PROLONGING AGENTS/GATIFLOXACIN
  • POSSIBLE QT PROLONGING AGENTS/DOFETILIDE
  • POSSIBLE QT PROLONGING AGENTS/ARSENIC
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    Drug Survey

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.