Niacin-Simvastatin Tablet, Extended Release Multiphase 24 Hr (Tablet, ER Hr) Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • Muscle Pain

If experienced, these tend to have a Less Severe expression

  • A Common Cold
  • A Skin Rash
  • An Infection
  • Constipation
  • Cough
  • Diarrhea
  • Dizziness
  • Head Pain
  • Heartburn
  • Indigestion
  • Intense Abdominal Pain
  • Itching
  • Nausea
  • Temporary Redness Of Face And Neck
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Atrial Fibrillation

If experienced, these tend to have a Less Severe expression

  • A Type Of Skin Condition With Redness And Itching Called Eczema
  • A Type Of Stomach Irritation Called Gastritis
  • Abnormal Heart Rhythm
  • Arthritis
  • Backache
  • Decreased Blood Platelets
  • Dizziness
  • Dry Skin
  • Fainting
  • Flu-Like Symptoms
  • Gas
  • Heart Throbbing Or Pounding
  • High Amount Of Uric Acid In The Blood
  • High Blood Sugar
  • Inflammation Of The Tissue Lining The Sinuses
  • Joint Pain
  • Low Amount Of Phosphate In The Blood
  • Low Energy
  • Muscle Pain
  • Stomach Cramps
  • Worsening Of A Peptic Ulcer

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Condition With Symptoms That Resemble Lupus
  • A Disease With Shrinking And Weaker Muscles Called Myopathy
  • A Low Number Of Red Blood Cells In The Blood Called Anemia
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Spasm Of The Larynx
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Disorder Where The Red Blood Cells Burst
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Liver Function Tests
  • Bronchitis
  • Chest Pain
  • Chronic Inflammation Of Muscles In The Body Called Polymyositis
  • Clouding Of The Lens Of The Eye Called Cataracts
  • Damage To The Liver And Inflammation
  • Decreased Blood Platelets
  • Diabetes
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Hives
  • Immune-Mediated Necrotizing Myopathy
  • Increased Eosinophils In The Blood
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Skin And Muscle
  • Inflammation Of The Skin With Blisters
  • Large Purple Or Brown Skin Blotches
  • Liver Failure
  • Liver Tissue Death
  • Lung Tissue Problems
  • Macular Edema
  • Muscle Inflammation
  • Muscle Pain And Stiffness In The Shoulder, Neck And Pelvis
  • Numbness And Tingling
  • Pancreatitis
  • Paralysis Of Some Or All Of The Muscles Of The Eye
  • Trouble Breathing
  • Urinary Tract Infection
  • Visible Water Retention

If experienced, these tend to have a Less Severe expression

  • A Decrease In The Blood Clotting Protein Prothrombin
  • A Feeling Of General Discomfort Called Malaise
  • A Migraine Headache
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • A Skin Rash
  • Abnormal Sensations Of The Skin
  • Altered Interest In Having Sexual Intercourse
  • An Increased Need To Urinate Often
  • Anxious Feelings
  • Blurred Vision
  • Burping
  • Chills
  • Confusion
  • Cough
  • Cramps
  • Decreased Appetite
  • Depression
  • Difficult Or Painful Urination
  • Difficulty Sleeping
  • Dry Mouth
  • Dry Skin
  • Enlarged Breasts
  • Excessive Sweating
  • Fever
  • Gas
  • Generalized Weakness
  • Generalized Weakness
  • Hair Loss
  • Heart Throbbing Or Pounding
  • High Blood Sugar
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation Of The Nose
  • Itching
  • Low Blood Pressure
  • Memory Loss
  • Muscle Spasm
  • Muscle Tremors
  • Muscle Weakness
  • Nervousness
  • Numbness
  • Numbness And Tingling
  • Orthostatic Hypotension, A Form Of Low Blood Pressure
  • Paralysis Of Nerves For The Face
  • Sensation Of Spinning Or Whirling
  • Skin Discoloration
  • Skin Nodules
  • Taste Impairment
  • Temporary Redness Of Face And Neck
  • The Inability To Have An Erection
  • Urination During The Night
  • Visible Water Retention
  • Vomiting

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.