COMMON side effects

If experienced, these tend to have a Severe expression i

• anemia
• decreased blood platelets
• low levels of white blood cells
• low levels of a type of white blood cell called neutrophils
• fever
• pain
• trouble breathing
• diarrhea

If experienced, these tend to have a Less Severe expression i

• stomatitis, a condition with painful swelling and sores inside the mouth
• constipation
• hair loss
• joint pain
• low energy
• excessive sweating
• decreased appetite
• headache
• cough
• nausea
• vomiting
• stomach cramps
• a feeling of pins and needles on skin
• low energy and weakness
• generalized weakness
• a feeling of general discomfort called malaise

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

• an infection
• pneumonia
• blockage of the stomach or intestine
• high amount of bilirubin in the blood

If experienced, these tend to have a Less Severe expression i

• an earache
• pain with menstruation
• bone pain
• chills
• chest pain
• abnormal liver function tests
• neuropathic pain

RARE side effects

If experienced, these tend to have a Severe expression i

• a systemic inflammatory response called sepsis due to an infection with bacteria
• a type of blood disorder with a decrease in all types of blood cells called pancytopenia
• bleeding
• inflammation of the small and large intestine
• inflammation of the skin due to an allergy
• itching
• a skin rash
• a significant type of allergic reaction called anaphylaxis
• a type of allergic reaction called angioedema
• a rupture in the wall of the stomach or intestine
• lung tissue problem
• neutropenic colitis

If experienced, these tend to have a Less Severe expression i

• pain with sexual intercourse
• peripheral sensory nerve disorder