Sibutramine/Antidepressants Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Both sibutramine and your antidepressant can affect your central nervous system.

What might happen:

You might have more side effects than normal.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) right away about taking these medicines together. Let your doctor know if you have any side effects from your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Meridia (sibutramine hydrochloride monohydrate) Canadian prescribing information. Abbott Limited December, 2004.
  • 2.Reductil (sibutramine hydrochloride) Australian prescribing information. Abbott Australasia Pty. Ltd. March 5, 2004.
  • 3.Reductil (sibutramine hydrochloride monohydrate) UK summary of product characteristics. Abbott Laboratories, Limited January 12, 2005.