If you are:
Only When Necessary: NON-TERATOGENIC COMPLICATIONS (RESP, GI,CNS) WITH EXPOSURE DURING 3RD TRIMESTER
Precaution: INSUFFICIENT HUMAN DATA AVAILABLE
An adult over 60:
management or monitoring precaution: Endocrine-Increased risk of hyponatremia and SIADH which may increase fall risk. Renal-Decrease dose by 50% for CrCL less than 30 mL/min. Cardiovascular-May elevate blood pressure and increase heart rate. Caution with underlying cardiovascular disease.
Giving Savella to a child under 12:
Severe Precaution: Possible increased suicidal ideation and attempt. Not approved or recommended for pediatric use.