What should I Know Regarding Pregnancy, Nursing and Administering Tapentadol Oral to Children or the Elderly?

If you are pregnant

  • Not Recommended:

    • If you are nursing

  • Precaution: LOW MW, MAY BE EXCRETED; MONITOR FOR INFANT WITHDRAWAL SYMPTOMS

    • If you are an adult over 60

  • management or monitoring precaution: Pulmonary-DO NOT USE in opioid intolerance. Life-threatening respiratory depression due to reduced clearance. Use cautiously with respiratory disease, when initiating, titrating and giving with other respiratory depressants. Consider naloxone Rx. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Gastrointestinal-Increased rate of constipation in the elderly. Cardiovascular-Vasodilation may predispose to orthostatic hypotension.

    • Pediatric use

  • Severe Precaution: Risk of respiratory depression. Safety and efficacy not established. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
    • Full Drug Information

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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.