Does MULTAQ Interact with other Medications?

Severe Interactions

These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • DRONEDARONE/STRONG CYP3A4 INHIBITORS; ATAZANAVIR; DARUNAVIR
  • DRONEDARONE/QT PROLONGING AGENTS
  • SELECTED CYP3A4 SUBSTRATES/MIFEPRISTONE
  • DRONEDARONE/MOBOCERTINIB
  • DRONEDARONE/IVABRADINE
  • STRONG & MOD 3A4 INHIB THAT PROLONG QT/CILOSTAZOL (> 50 MG)
  • SELECTED CYP3A4 MODERATE INHIBITORS/LURASIDONE (> 80 MG)
  • STRONG AND MODERATE CYP3A4 INHIBITORS/ASUNAPREVIR
  • QT PROLONGING AGENTS/HYDROXYCHLOROQUINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/LOMITAPIDE
  • SELECTED CLASS I & CLASS III ANTIARRHYTHMIC AGENTS/SOTALOL
  • SLT STRONG & MOD CYP2D6 INHIBIT THAT PROLONG QT/THIORIDAZINE
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (> 12.5 MG)
  • QT PROLONGING AGENTS/ANAGRELIDE
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (> 500 MG BID)
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (> 50 MG)
  • STRONG OR MODERATE CYP3A4 INHIBITORS/FLIBANSERIN
  • CLASS IA AND III ANTIARRHYTHMIC AGENTS/FINGOLIMOD
  • DRONEDARONE/LOVASTATIN (> 20 MG); SIMVASTATIN(> 10 MG)
  • CLASS IA AND III ANTIARRHYTHMICS/IBUTILIDE
  • SELECTED CLASS IA AND III ANTIARRHYTHMICS/PROPAFENONE
  • CLASS IA AND CLASS III ANTIARRHYTHMICS/DOFETILIDE
  • SELECTED CLASS IA & III ANTIARRHYTHMICS/CISAPRIDE
  • SELECTED CLASS I & III ANTIARRHYTHMICS/MIZOLASTINE
  • SELECTED ANTIARRHYTHMICS/PIMOZIDE
  • CLASS I AND III ANTIARRHYTHMICS/HALOFANTRINE
  • CLASS IA & III ANTIARRHYTHMICS/SELECTED QUINOLONES
  • Serious Interactions

    These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • AMIODARONE; DRONEDARONE/DIGITALIS GLYCOSIDES
  • SELECTED ANTIARRHYTHMICS/QUINUPRISTIN-DALFOPRISTIN
  • DRONEDARONE/POSSIBLE QT PROLONGING AGENTS
  • AMIODARONE; DRONEDARONE/RIFAMPIN; RIFAPENTINE
  • AMIODARONE;DRONEDARONE/SELECTED STRONG CYP3A4 INDUCERS
  • AMIODARONE; DRONEDARONE/ST. JOHN'S WORT
  • SELECT SENSITIVE CYP3A4 SUBSTRATES THAT PROLONG QT/VOXELOTOR
  • DRONEDARONE/ATAZANAVIR; FOSAMPRENAVIR
  • MODERATE CYP3A4 INHIBITORS/MAVACAMTEN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/PACRITINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/BILASTINE
  • STRONG & MODERATE 3A4 INHIB THAT PROLONG QT/ENCORAFENIB
  • SELECTED QT PROLONGING AGENTS/INTRAVENOUS LEFAMULIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/DOXORUBICIN
  • STRONG & MODERATE 3A4 INHIBITOR THAT PROLONG QT/FEXINIDAZOLE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/INFIGRATINIB
  • SELECTED MODERATE CYP3A4 INHIBITORS/ALPRAZOLAM
  • MODERATE CYP3A4 INHIBITORS/VOCLOSPORIN
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/RELUGOLIX
  • QT PROLONGING AGENTS/LEVOMEPROMAZINE
  • DRONEDARONE/IVOSIDENIB
  • DUAL CYP2D6 AND CYP3A4 INHIBITORS/ELIGLUSTAT
  • SELECT MODERATE CYP2D6 INHIBITORS/TAMOXIFEN
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LURBINECTEDIN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/SELPERCATINIB
  • DRONEDARONE/PEXIDARTINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/PEMIGATINIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/SELUMETINIB
  • P-GP OR BCRP INHIBITORS THAT PROLONG QT/PAZOPANIB
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LUMATEPERONE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/LEMBOREXANT
  • MODERATE CYP3A4 INHIBITORS/ELEXACAFTOR-TEZACAFTOR-IVACAFTOR
  • STRONG & MOD CYP3A4 INHIBITOR THAT PROLONG QT/ORAL LEFAMULIN
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/ENTRECTINIB
  • DRONEDARONE/TACROLIMUS
  • MODERATE CYP3A4 INHIBITORS/BRIGATINIB
  • QT PROLONGING AGENTS/GLASDEGIB
  • QT PROLONGING AGENTS/LOFEXIDINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/TEZACAFTOR-IVACAFTOR
  • QT PROLONGING AGENTS/MACIMORELIN
  • QT PROLONGING AGENTS/INOTUZUMAB OZOGAMICIN
  • STRONG CYP3A4 INHIB;MODERATE 3A4 & P-GP DUAL INHIB/NERATINIB
  • MODERATE CYP3A4 INHIBITORS THAT PROLONG QT/QUETIAPINE
  • STRONG AND MODERATE CYP3A4 INHIBITORS/DEFLAZACORT
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/COLCHICINE
  • QT PROLONGING AGENTS/HYDROXYZINE
  • QT PROLONGING AGENTS/PIMAVANSERIN
  • MODERATE CYP3A4 INHIBITORS/VENETOCLAX
  • QT PROLONGING AGENTS/GADOFOSVESET
  • QT PROLONGING AGENTS/BEDAQUILINE
  • QT PROLONGING AGENTS/OSIMERTINIB
  • SELECTED P-GP INHIBITORS/EDOXABAN (> 30 MG)
  • SELECTED CLASS IA & III ANTIARRHYTHMICS/SELECTED QUINOLONES
  • MODERATE CYP3A4 INHIBITORS/NALOXEGOL (<= 12.5 MG)
  • MODERATE CYP3A4 INHIBITORS/COBIMETINIB; OLAPARIB; SONIDEGIB
  • SELECTED P-GP AND MODERATE CYP3A4 INHIBITORS/RIVAROXABAN
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (> 10 MG)
  • MODERATE CYP3A4 INHIBITORS/ERGOT ALKALOIDS
  • QT PROLONGING AGENTS/TRAZODONE (>= 100 MG)
  • STRONG & MODERATE CYP3A4 INHIBITORS/GUANFACINE
  • STRONG OR MODERATE CYP3A4 INHIBITORS/SIMEPREVIR
  • STRONG AND MODERATE CYP3A4 INHIBITORS/BOSENTAN
  • CLASS I & CLASS III ANTIARRHYTHMICS/VERNAKALANT
  • STRONG AND MODERATE CYP3A4 INHIBITORS/IVACAFTOR
  • DRONEDARONE, KETOCONAZOLE/DABIGATRAN
  • QT PROLONGING AGENTS/TOREMIFENE
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/TOPOTECAN
  • Moderate Interactions

    These medications may cause some risk when taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

  • DRONEDARONE/DILTIAZEM; NIFEDIPINE; VERAPAMIL
  • DRONEDARONE/COUMARIN ANTICOAGULANTS
  • SELECTED SENSITIVE CYP3A4 SUBSTRATES/SCHISANDRA
  • MODERATE CYP3A4 INHIBITORS/MITAPIVAT
  • MODERATE CYP3A4 INHIBITORS/DARIDOREXANT
  • QT PROLONGING AGENTS/OZANIMOD
  • QT PROLONGING AGENTS/PONESIMOD
  • QT PROLONGING AGENTS/SIPONIMOD
  • MODERATE CYP3A4 INHIBITORS/RIMEGEPANT
  • MODERATE CYP3A4 INHIBITORS/TAZEMETOSTAT
  • MODERATE CYP3A4 INHIBITORS/AVAPRITINIB
  • MODERATE CYP3A4 INHIBITORS/UBROGEPANT
  • MODERATE CYP3A4 INHIBITORS/ZANUBRUTINIB
  • SELECTED CYP3A4 MODERATE INHIBITORS/LURASIDONE (<= 80 MG)
  • QT PROLONGING AGENTS/PITOLISANT
  • SODIUM CHANNEL BLOCKER; POTASSIUM CHANNEL BLOCKER/LACOSAMIDE
  • QT PROLONGING AGENTS/GILTERITINIB
  • MODERATE CYP3A4 INHIBITORS/ABEMACICLIB
  • SELECTED P-GP INHIBITORS/EDOXABAN (<= 30 MG)
  • QT PROLONGING AGENTS/TRAZODONE (< 100 MG)
  • MODERATE CYP3A4 INHIBITORS/CABERGOLINE
  • SELECTED MODERATE CYP3A4 INHIBITORS/ACALABRUTINIB
  • SELECTED P-GLYCOPROTEIN (P-GP) INHIBITORS/BETRIXABAN
  • QT PROLONGING AGENTS/EFAVIRENZ
  • MODERATE CYP3A4 INHIBITORS/BROMOCRIPTINE
  • MODERATE CYP3A4 INHIBITORS/BREXPIPRAZOLE
  • P-GP AND MODERATE CYP3A4 INHIBITORS/APIXABAN
  • P-GP AND SELECTED CYP3A4 INHIBITORS/NINTEDANIB
  • MODERATE CYP3A4 INHIBITORS/SUVOREXANT (<= 10 MG)
  • DILTIAZEM;DRONEDARONE;VERAPAMIL/TAMSULOSIN
  • MODERATE CYP3A4 INHIBITORS/AVANAFIL (<= 50 MG)
  • MODERATE CYP3A4 INHIBITORS/IBRUTINIB
  • P-GLYCOPROTEIN (P-GP) INHIBITORS/AFATINIB
  • AMIODARONE; DRONEDARONE/SIROLIMUS
  • DRONEDARONE/ATORVA; LOVA (<=20MG); SIMVASTATIN (<=10MG)
  • SELECTED MODERATE TO STRONG CYP2D6 INHIBITORS/TRAMADOL
  • SELECTED MODERATE CYP3A4 INHIBITORS/SELECTED OPIOIDS
  • MODERATE CYP3A4; P-GP INHIBITORS/EVEROLIMUS
  • MODERATE CYP3A4 INHIBITORS/RANOLAZINE (<=500 MG BID)
  • CYP3A4; CYP2C8; P-GLYCOPROTEIN (P-GP) INHIBITORS/LOPERAMIDE
  • AMIODARONE; DRONEDARONE/SELECTED BETA-BLOCKERS
  • STRONG & MOD 3A4 INHIB THAT PROLONG QT/CILOSTAZOL (<=50MG)
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.