SAPHRIS Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • extrapyramidal disease, a type of movement disorder
  • a feeling of restlessness with inability to sit still

If experienced, these tend to have a Less Severe expression i

  • drowsiness
  • dizziness
  • difficulty sleeping
  • reduced sensation in the mouth

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • high blood pressure

If experienced, these tend to have a Less Severe expression i

  • high cholesterol
  • high amount of triglyceride in the blood
  • excessive saliva production
  • dry mouth
  • indigestion
  • constipation
  • joint pain
  • low energy
  • pain
  • muscle tremors
  • taste impairment
  • weight gain
  • increased hunger
  • headache
  • vomiting
  • irritability
  • intense abdominal pain
  • anxious feelings

RARE side effects

If experienced, these tend to have a Severe expression i

  • diabetes
  • low amount of sodium in the blood
  • anemia
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • suicidal thoughts
  • tardive dyskinesia, a disorder characterized by involuntary movements of the face, mouth and tongue
  • neuroleptic malignant syndrome, a reaction characterized by fever, muscle rigidity and confusion
  • bundle branch block
  • slow heartbeat
  • prolonged QT interval on EKG
  • low blood pressure
  • seizures
  • sleep apnea
  • swelling of the tongue
  • trouble breathing
  • difficulty swallowing
  • high blood sugar
  • heat stroke
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • accidental falls
  • problems with food passing through the esophagus
  • a choking feeling
  • a type of significant allergic skin reaction called DRESS syndrome
  • fast heartbeat

If experienced, these tend to have a Less Severe expression i

  • a high prolactin level
  • confusion
  • double vision
  • blurred vision
  • orthostatic hypotension, a form of low blood pressure
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • gastroesophageal reflux disease
  • the inability to have an erection
  • enlarged breasts
  • breastmilk production not associated with childbirth or nursing
  • absence of menstrual periods
  • fainting
  • abnormal manner of walking
  • a skin rash
  • a type of speech disorder called dysarthria
  • a sensation of feeling warm

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.