VOTRIENT Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • decreased blood platelets
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • high blood pressure
  • slow heartbeat
  • a blood clot
  • bleeding

If experienced, these tend to have a Less Severe expression i

  • stomatitis, a condition with painful swelling and sores inside the mouth
  • hair loss
  • bleached hair
  • muscle pain
  • low energy
  • pain
  • a skin rash
  • decreased appetite
  • weight loss
  • headache
  • trouble breathing
  • nausea
  • vomiting
  • diarrhea
  • elevation of proteins in the urine
  • generalized weakness
  • high blood levels of the lipase enzyme
  • pain in the muscles or bones

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • an infection
  • a condition with low thyroid hormone levels
  • a decreased number of lymphocytes in the blood
  • a heart attack
  • a blood clot in an artery
  • high amount of bilirubin in the blood
  • a high alanine transaminase level
  • a high aspartate transaminase level

If experienced, these tend to have a Less Severe expression i

  • blurred vision
  • indigestion
  • urinary tract infection
  • a nail disorder
  • dry skin
  • skin discoloration
  • decreased pigmentation of the skin
  • difficulty sleeping
  • excessive sweating
  • chills
  • taste impairment
  • erythrodysesthesia or tingling, pain, redness, and edema in the hands and feet
  • a change in voice
  • nosebleed
  • gas
  • a feeling of pins and needles on skin
  • intense abdominal pain

RARE side effects

If experienced, these tend to have a Severe expression i

  • hemolytic uremic syndrome, a condition that affects the kidney and the blood
  • detachment of the retina of the eye
  • extremely high blood pressure
  • torsades de pointes, a type of abnormal heart rhythm
  • prolonged QT interval on EKG
  • chronic heart failure
  • left ventricular heart failure
  • a hemorrhage in the brain
  • a stroke
  • a localized weakening and ballooning in an artery wall called an arterial aneurysm
  • an occurrence of a blood clot in an artery
  • thrombotic thrombocytopenic purpura, a type of blood disorder
  • blood clot formation in vein
  • the presence of air or gas in the lung
  • a type of inflammation of the lung called interstitial pneumonitis
  • a gastrointestinal tract fistula
  • liver failure
  • inflammation of the liver called hepatitis
  • bleeding of the stomach or intestines
  • coughing up of blood
  • impaired wound healing
  • a rupture in the wall of the stomach or intestine
  • bleeding from the lungs
  • lung tissue problem
  • reactivation of hepatitis B infection
  • pancreatitis
  • abnormal increase in red blood cells
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • a fistula between two body organs
  • dissection of artery
  • heart failure with reduced ejection fraction
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • angina, a type of chest pain
  • bloody urine
  • joint pain
  • muscle spasm
  • puffy face from water retention

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.