What should I Know Regarding Pregnancy, Nursing and Administering Ondansetron HCL-D5W Solution, Intravenous Piggyback to Children or the Elderly?

If you are PREGNANT

  • Requires a Risk/Benefit Assessment:

If you are NURSING


If you are an adult over 60

  • management or monitoring precaution: Cardiovascular- Limit initial IV doses to no more than 8 mg for age>74 and no more than 16 mg for ages 66-74. Subsequent doses must not exceed 8 mg and given no sooner than 4-8 hours later. Infuse over a minimum of 15 min. The elderly are more prone to QT prolongation due to multiple meds and iatrogenic hypokalemia, hypomagnesemia; correct electrolytes before giving oral or IV ondansetron. Neuro/Psych-The elderly may be more prone to extrapyramidal reactions associated with IV doses.

Giving Ondansetron HCL-D5W Solution, Intravenous Piggyback to a child under 12

  • Severe Precaution: Limited information age < 30 days. Longer half-life in infants. Monitor closely.
  • Severe Precaution: Longer half-life in age < 4 months. Monitor closely.

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