What should I Know Regarding Pregnancy, Nursing and Administering Vemurafenib Tablet to Children or the Elderly?
If you are PREGNANT
- Not Recommended: POTENTIAL HARM BASED ON MECHANISM OF ACTION; CROSSES PLACENTA
If you are NURSING
- Absolute Contraindication: POTENTIAL FOR SERIOUS ADVERSE EFFECTS
If you are an adult over 60
- management or monitoring precaution: General-May have increased incidence of certain adverse events: cutaneous squamous cell carcinoma, keratoacanthoma. Gastrointestinal-May have increased incidence of anorexia and nausea. Cardiovascular-May have increased adverse event risk of atrial fibrillation or QT prolongation.
Giving Vemurafenib Tablet to a child under 12
- management or monitoring precaution: Safety and efficacy not established in adolescents with unresectable or metastatic melanoma with BRAF V600 mutation.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.