Who should not take Promethazine VC?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • decreased function of bone marrow
  • Parkinson Symptoms
  • Neuroleptic Malignant Syndrome
  • Lower Seizure Threshold
  • closed angle glaucoma
  • Very Rapid Heartbeat - Torsades de Pointes
  • prolonged QT interval on EKG
  • Abnormal EKG with QT changes from Birth
  • Decreased Lung Function
  • Stenosing Peptic Ulcer
  • Narrowing of Opening Between Stomach and Small Intestine
  • Stomach or Intestine Blockage
  • liver problems
  • Blockage of Urinary Bladder
  • Enlarged Prostate
  • Coma
  • seizures
  • Temporarily Stops Breathing While Sleeping
  • High Amount of Bilirubin in the Blood
  • Chronic Obstructive Lung Disease
  • chronic idiopathic constipation
  • overactive thyroid gland
  • Acidosis
  • high blood pressure
  • Severe Uncontrolled High Blood Pressure
  • heart attack
  • coronary artery disease
  • Partial Heart Block
  • Rapid Ventricular Heartbeat
  • Slow Heartbeat
  • chronic heart failure
  • Severe Hardening of the Arteries
  • Blood Clot in an Artery
  • acute inflammation of the liver
  • Acute Inflammation of the Pancreas
  • decreased oxygen in the tissues or blood


  • Phenothiazines
  • Sympathomimetic Agents
  • Ephedrine Analogues

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, expect as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.