What should I Know Regarding Pregnancy, Nursing and Administering JAKAFI to Children or the Elderly?

If you are pregnant

  • Not Recommended:
  • If you are nursing

  • Precaution: MFG REC AVOID BREASTFEEDING DURING TX AND 2 WKS AFTER PO AND 4 WKS AFTER TOP
  • If you are an adult over 60

  • management or monitoring precaution: Renal-Dose adjustment is required for CrCL<60 mL/min. Hepatic-Dose adjustment required for any hepatic impairment. Consider the hepatic impairment of aging.
  • Pediatric use

  • Severe Precaution: Safety and efficacy not established for age < 12 years. Increased risk of bone fractures seen in animal studies.
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    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.