Hormonal Contraceptives/Mycophenolate Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

How this interaction occurs is not known.

What might happen:

Mycophenolate may decrease the amount of your hormonal contraceptive in your blood, making it less effective.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Unless you are practicing abstinence, you should use two reliable forms of birth control beginning four weeks prior to starting mycophenolate, while you are taking mycophenolate, and for six weeks after you stop taking mycophenolate.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.CellCept (mycophenolate mofetil) US prescribing information. Roche Pharmaceuticals July, 2015.
  • 2.Birgerson LE. Dear Health Care Professional letter Subject: Important changes in the CellCept (mycophenolate mofetil) prescribing information - Use of CellCept is associated with increased pregnancy loss and cogential malformations/change from. pregnancy category C to pregnancy category D. Roche Pharmaceuticals October, 2007.