Who should not take QSYMIA?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • overactive thyroid gland
  • diabetes
  • psychotic disorder
  • alcoholism
  • drug abuse
  • glaucoma, an increased pressure in the eye
  • significant uncontrolled high blood pressure
  • mild high blood pressure
  • heart attack within the last 30 days
  • angina, a type of chest pain
  • abnormal heart rhythm
  • chronic heart failure
  • decreased kidney function
  • pregnancy
  • a patient who is producing milk and breastfeeding
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • history of stroke
  • excess body acid
  • confusion
  • suicidal thoughts
  • depression
  • increased pressure in the eye
  • a decrease in sharpness of vision called reduced visual acuity
  • liver problems
  • kidney stones
  • difficulty concentrating
  • memory loss
  • fever
  • diarrhea
  • pregnancy
  • secondary angle-closure glaucoma, a type of eye disorder
  • a feeling of pins and needles on skin
  • inherited deficiency of argininosuccinate lyase
  • inherited carbamoyl phosphate synthetase deficiency
  • citrullinemia
  • ornithine carbamoyltransferase deficiency
  • arginase deficiency
  • hyperammonemia associated with N-acetylglutamate synthase deficiency
  • chronic kidney disease stage 3A (moderate)
  • chronic kidney disease stage 3B (moderate)
  • kidney disease with likely reduction in kidney function

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.