Vardenafil (> 5 mg)/Selected CYP3A4 Inhibitors Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Severe. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Some medicines slow down how quickly your liver processes vardenafil.

What might happen:

The amount of vardenafil in your blood may increase and cause harmful effects.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) right away about using these medicines together. If your doctor decides that it is safe for you to use these medicines together, you may need to decrease the dose of vardenafil you can safely take. Discuss this with your doctor or pharmacist. Contact your doctor if you experience a painful or prolonged erection, fainting, dizziness, or changes in vision.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Levitra (vardenafil hydrochloride) US prescribing information. Bayer Pharmaceuticals Corporation September, 2015.
  • 2.Levitra (vardenafil hydrochloride trihydrate) Australian prescribing information. Bayer Australia Limited November 2, 2006.
  • 3.Levitra (vardenafil hydrochloride) Canadian prescribing information. Bayer, Inc. October 24, 2006.
  • 4.Levitra (vardenafil hydrochloride trihydrate) UK summary of product characteristics. Bayer plc December 20, 2006.