NORETHINDRON-ETHINYL ESTRADIOL Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • irregular periods
  • bleeding not related to menstrual period
  • abdominal bloating
  • If experienced, these tend to have a Less Severe expression i

  • water retention
  • breast pain
  • acne
  • dizziness
  • headache
  • nausea
  • abdominal bloating
  • inflammation or infection of the vagina
  • muscle pain
  • low energy
  • visible water retention
  • weight loss
  • a yeast infection of the vagina and vulva
  • inflammation of the tissue lining the sinuses
  • pain with menstruation
  • decreased breast milk production
  • decreased appetite
  • weight gain
  • stomach cramps
  • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • excessive fat in the blood
  • high blood pressure
  • blood clot in a deep vein of the extremities
  • overgrowth of the uterine lining
  • inflammation of the lining of the stomach and intestines
  • If experienced, these tend to have a Less Severe expression i

  • altered interest in having sexual intercourse
  • throat irritation
  • bronchitis
  • urinary tract infection
  • enlarged breasts
  • abnormally long or heavy periods
  • increased sensitivity of the skin to the sun
  • yellow-brown patches on skin
  • weight gain
  • weight loss
  • vomiting
  • stomach cramps
  • abnormal glucose tolerance test results
  • intense abdominal pain
  • indigestion
  • vaginal discharge
  • an abnormal increase in muscle tone
  • dizziness
  • ectropion of cervix, where cells normally inside the cervix spread to the outer cervical surface
  • mood changes
  • a migraine headache
  • headache
  • diarrhea
  • RARE side effects

    If experienced, these tend to have a Severe expression i

  • benign hepatic cell adenoma, a type of liver tumor
  • a breast tumor
  • high amount of triglyceride in the blood
  • hemolytic uremic syndrome, a condition that affects the kidney and the blood
  • a clot in the small veins that carry blood to or from the retina of the eye
  • clouding of the lens of the eye called cataracts
  • sudden blindness and pain upon moving the eye
  • a heart attack
  • a clot in the lung
  • abnormal bleeding in the brain resulting in damage to brain tissue, called a hemorrhagic stroke
  • a stroke
  • obstruction of a blood vessel by a blood clot
  • a blood clot in an artery
  • a blood clot in a vein of the liver
  • a blood clot
  • inflammation of the large intestine
  • inflammation of the liver called hepatitis
  • gallstones
  • disease of the gallbladder
  • a blockage of the bile duct that resulting in high bilirubin levels
  • decreased kidney function
  • an ovarian cyst
  • unconsciousness
  • trouble breathing
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • generalized weakness
  • pancreatitis
  • cervical dysplasia, the development of abnormal cells in the cervix
  • a liver tumor
  • liver cell carcinoma
  • focal nodular hyperplasia of liver, a type of liver tumor
  • an acute blockage of the mesenteric vein
  • a clot or thrombosis of the mesenteric artery of the intestines
  • cancer of the ovary
  • depression
  • high blood pressure
  • thrombophlebitis, an inflamed vein due to a blood clot
  • breastmilk production not associated with childbirth or nursing
  • abnormally long or heavy periods
  • pregnancy to occur outside of womb
  • erythema multiforme, a type of allergic skin reaction
  • erythema nodosum, a skin condition with red and painful nodules
  • itching
  • abnormal liver function tests
  • cancer in the lining of the uterus
  • low amount of calcium in the blood
  • blood clot in a deep vein of the extremities
  • the flu
  • a blockage in the gallbladder
  • a lump in the breast
  • hives
  • a change in the curvature of the cornea of the eye
  • involuntary muscle movements
  • If experienced, these tend to have a Less Severe expression i

  • mood changes
  • breastmilk production not associated with childbirth or nursing
  • inflammation or infection of the vagina
  • vaginal dryness
  • pain with menstruation
  • premenstrual syndrome
  • itching
  • hair loss
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • backache
  • muscle spasm
  • difficulty sleeping
  • low energy
  • a skin rash
  • visible water retention
  • fluid retention in the legs, feet, arms or hands
  • changes in appetite
  • diarrhea
  • pelvic pain
  • nervousness
  • a decrease in how often a woman menstruates
  • discharge of fluid from the cervix
  • anxious feelings
  • water retention
  • a migraine headache
  • constipation
  • breast pain
  • absence of menstrual periods
  • acne
  • hives
  • yellow-brown patches on skin
  • pain in the arms or legs
  • drowsiness
  • fever
  • weight gain
  • nausea
  • irritability
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.