Ethinyl Estradiol (Greater Than 20 mcg)/Glecaprevir-Pibrentasvir Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Each of these medicines has a chance of harming your liver.

What might happen:

The combination of these two medicines may increase the risk for liver problems. Signs of liver problems may include yellowing of the skin or eyes, dark urine, pale stools, or the onset of new/worsening nausea or vomiting, loss of appetite or weakness.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your health care provider may want to do periodic blood tests to check your liver function or change your medicines.Contact your doctor right away if you have yellowing of the skin or eyes, dark urine, pale stools, or the onset of new/worsening nausea or vomiting, loss of appetite or weakness.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Mavyret (glecaprevir and pibrentasvir) US prescribing information. AbbVie Inc. October, 2023.
  • 2.Maviret (glecaprevir and pibrentasvir) UK Summary of Product Characteristics. AbbVie Ltd. August, 2021.
  • 3.Maviret (glecaprevir and pibrentasvir) CA prescribing information. AbbVie Corporation November 28, 2018.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.