What should I Know Regarding Pregnancy, Nursing and Administering Xeljanz to Children or the Elderly?
Sorry, we have no data available. Please contact your doctor or pharmacist.
If you are PREGNANT
- FDB Only When Necessary: INSUFFICIENT HUMAN DATA AVAILABLE.
If you are NURSING
- Absolute Contraindication: AVOID BREASTFEEDING DURING TREATMENT AND FOR 18 HOURS AFTER LAST DOSE
If you are an adult over 60
- management or monitoring precaution: General-Serious infection rates are higher in the elderly. Monitor closely. Increased thromboembolic risk for patients receiving 10mg BID dosing. Cardiovascular-Increased risk of DVT/PE in patients with heart failure or prior heart failure, per European Medicines Agency. Renal-Reduce dose to 5 mg once daily for moderate-severe renal impairment. Hepatic-Reduce dose to 5 mg once daily for moderate hepatic impairment.
Giving Xeljanz to a child under 12
- management or monitoring precaution: No safety and efficacy established in pediatrics.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.