SKYLA Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • absence of menstrual periods
  • abnormally long or heavy periods
  • bleeding not related to menstrual period

If experienced, these tend to have a Less Severe expression i

  • acne
  • nausea
  • vomiting
  • vulvovaginitis, an inflammation or infection of the vagina and vulva

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • anemia
  • depression
  • enlargement of an ovary
  • a skin rash

If experienced, these tend to have a Less Severe expression i

  • mood changes
  • altered interest in having sexual intercourse
  • breast pain
  • inflammation of the cervix
  • vaginal discharge
  • pain with menstruation
  • a type of skin condition with redness and itching called eczema
  • itching
  • hair loss
  • hirsutism, a condition of hair growth on parts of the body normally without hair
  • backache
  • weight gain
  • headache
  • nervousness
  • intense abdominal pain
  • a decrease in how often a woman menstruates
  • drug-induced hot flashes

RARE side effects

If experienced, these tend to have a Severe expression i

  • a systemic inflammatory response called sepsis due to an infection with bacteria
  • an infection by Actinomyces bacteria called actinomycosis
  • breast cancer
  • a migraine headache
  • high blood pressure
  • a clot in the lung
  • a stroke
  • a blood clot in an artery
  • blood clot in a deep vein of the extremities
  • blood clot formation in vein
  • infection of female pelvic organs due to Streptococcus
  • an infection of the female reproductive organs called pelvic inflammatory disease
  • inflammation of the endometrium
  • pregnancy to occur outside of womb
  • a type of allergic reaction called angioedema
  • puncture of the uterus from the intra-uterine device
  • a blood infection with group A Streptococcus bacteria
  • expulsion of intrauterine contraceptive device

If experienced, these tend to have a Less Severe expression i

  • uterine cramps
  • a decrease in production of breast milk
  • hives
  • visible water retention
  • abdominal bloating
  • pain with sexual intercourse

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.