What should I Know Regarding Pregnancy, Nursing and Administering Kynamro Syringe to Children or the Elderly?

If you are PREGNANT

  • FDB Contraindicated or Not Recommended: FDA B; BASED ON DRUG PHARMACOLOGY; MAY INHIBIT FETAL CHOLESTEROL PRODUCTION

If you are NURSING

  • Precaution: INSUFFICIENT HUMAN DATA AVAILABLE

If you are an adult over 60

  • management or monitoring precaution: Hepatic-Increased incidence of hepatic steatosis reported. Measure liver-related tests (ALT and AST, at a minimum) prior to each increase in dose or monthly, whichever occurs first for the first year. Contraindicated in patients with moderate or severe hepatic impairment, or active liver disease, including unexplained persistent elevations of serum transaminases. Cardiovascular-Higher rate of hypertension and peripheral edema.

Giving Kynamro Syringe to a child under 12

  • management or monitoring precaution: No established safety and efficacy.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.