THALOMID Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

  • low amount of calcium in the blood
  • low levels of white blood cells
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • a disorder of the peripheral nerves that enable movement called peripheral motor neuropathy
  • obstruction of a blood vessel by a blood clot
  • trouble breathing

If experienced, these tend to have a Less Severe expression i

  • confusion
  • dry skin
  • muscle weakness
  • drowsiness
  • dizziness
  • low energy
  • muscle tremors
  • fluid retention in the legs, feet, arms or hands
  • weight gain
  • weight loss
  • headache
  • nausea
  • generalized weakness
  • anxious feelings

INFREQUENT side effects

If experienced, these tend to have a Severe expression i

  • thrush
  • an infection
  • high amount of bilirubin in the blood
  • intense abdominal pain

If experienced, these tend to have a Less Severe expression i

  • mood changes
  • agitation
  • orthostatic hypotension, a form of low blood pressure
  • dry mouth
  • joint pain
  • muscle pain
  • decreased appetite
  • increased hunger
  • diarrhea

RARE side effects

If experienced, these tend to have a Severe expression i

  • shingles
  • an unusual viral infection called cytomegalovirus infection
  • chronic myelocytic leukemia
  • a condition with low thyroid hormone levels
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • decreased blood platelets
  • low levels of a type of white blood cell called neutrophils
  • a decreased number of lymphocytes in the blood
  • suicidal behavior
  • hearing loss
  • a heart attack
  • a clot in the lung
  • pulmonary hypertension
  • abnormal heart electrical signals
  • sick sinus syndrome
  • slow heartbeat
  • abnormal heart rhythm
  • a transient ischemic attack, a type of stroke that lasts only a few minutes
  • a stroke
  • a blood clot in an artery
  • blood clot in a deep vein of the extremities
  • low blood pressure
  • escape of fluid into the lungs
  • blockage of the stomach or intestine
  • blockage of a bile duct
  • bleeding of the stomach or intestines
  • kidney failure
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • erythema nodosum, a skin condition with red and painful nodules
  • skin rash with sloughing
  • fainting
  • seizures
  • a significant drop in blood pressure due to bacterial infection
  • apnea, a breathing interruption
  • a significant type of allergic reaction called anaphylaxis
  • a type of allergic reaction called angioedema
  • a hypersensitivity reaction to a drug
  • a rupture in the wall of the stomach or intestine
  • reactivation of hepatitis B infection
  • progressive multifocal leukoencephalopathy, a type of brain infection
  • a type of brain disorder called posterior reversible encephalopathy syndrome
  • a type of significant allergic skin reaction called DRESS syndrome
  • tumor lysis syndrome

If experienced, these tend to have a Less Severe expression i

  • depression
  • double vision
  • blurred vision
  • pink eye
  • nystagmus, a condition with involuntary eye movements
  • Raynaud's phenomenon, a condition where blood vessels constrict too much with coldness or stress
  • canker sores
  • absence of menstrual periods
  • a nail disorder
  • hives
  • leg cramps
  • a long period of feeling drowsy or sleepy
  • flu-like symptoms
  • taste impairment
  • involuntary leakage of urine
  • decreased urine production

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.