Sarilumab; Tocilizumab/Biologic DMARDs Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Sarilumab, tocilizumab, and your other medicine affect how your immune system works.
What might happen:
Using these medicines together increases your risk of a life-threatening infection.
What you should do about this interaction:
Let sure your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together. Let your doctor know right away if you develop any fatigue, shortness of breath, cough, blood in phlegm, chills, aches, fever, nausea, vomiting, diarrhea, weakness, weight loss, burning when urinating or the need to urinate more often, or a painful rash/blisters.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Kevzara (sarilumab) Canadian product monograph. Sanofi-aventis Canada Inc. January 12, 2017.
- 2.Actemra (tocilizumab) US prescribing information. Genentech, Inc. September, 2018.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.