Piperacillin-Tazobactam Vial

COMMON BRAND(S): Zosyn

GENERIC NAME(S): Piperacillin-Tazobactam

OTHER NAME(S): Piperacillin-Tazobactam Solution, Reconstituted (Recon Soln)

Uses

Uses

Piperacillin/tazobactam is used to treat a wide variety of bacterial infections. It is a penicillin antibiotic. It works by stopping the growth of bacteria.

How to use Piperacillin-Tazobactam Vial

This medication is given by injection into a vein as directed by your doctor, usually every 6 hours. It should be injected slowly over at least 30 minutes. The dosage is based on your medical condition and response to treatment. For children, the dosage is also based on age and weight.

If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.

If you are using the frozen pre-mixed solution, thaw the container at room temperature or in the refrigerator. If the bag is thawed in the refrigerator, let it sit at room temperature for at least 1 hour before using. Do not thaw by putting in warm/hot water or microwaving. After thawing, shake well and squeeze the container to check for leaks. Discard if the container leaks. Do not re-freeze the solution after thawing.

For the best effect, use this antibiotic at evenly spaced times. To help you remember, use this medication at the same time(s) every day.

Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.

Side Effects

Side Effects

Nausea, constipation, diarrhea, headache, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding.

This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool.

Do not use anti-diarrhea or opioid medications if you have any of these symptoms because these products may make them worse.

Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.

Get medical help right away if you have any very serious side effects, including: seizures, signs of kidney problems (such as a change in the amount of urine).

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: fever that doesn't go away, new or worsening lymph node swelling, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Precautions

Precautions

Before using piperacillin/tazobactam, tell your doctor or pharmacist if you are allergic to it; or to other antibiotics (such as penicillins, cephalosporins); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: cystic fibrosis, kidney disease.

This medication contains sodium. Consult your doctor or pharmacist if you are on a salt-restricted diet or if you have a condition that could be worsened by an increase in salt intake (such as heart failure, high blood pressure).

Piperacillin/tazobactam may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not have any immunizations/vaccinations while using this medication unless your doctor tells you to.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the extra sodium in this medication.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This medication passes into breast milk in small amounts. Consult your doctor before breast-feeding.

Interactions

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

One product that may interact with this drug is: methotrexate.

Although most antibiotics are unlikely to affect hormonal birth control such as pills, patch, or ring, a few antibiotics (such as rifampin, rifabutin) can decrease their effectiveness. This could result in pregnancy. If you use hormonal birth control, ask your doctor or pharmacist for more details.

This medication may interfere with certain lab tests (including certain urine glucose tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.

Overdose

Overdose

If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: seizures.

Notes

Lab and/or medical tests (such as complete blood count, sodium/potassium blood levels, kidney/liver function tests) should be done while you are using this medication. Keep all medical and lab appointments.

Missed Dose

For the best possible benefit, it is important to receive each scheduled dose of this medication as directed. If you miss a dose, contact your doctor or pharmacist right away to establish a new dosing schedule. Do not double the dose to catch up.

Storage

Consult the product instructions or your pharmacist for storage details. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised May 2018. Copyright(c) 2018 First Databank, Inc.

Images
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piperacillin-tazobactam 3.375 gram intravenous solution
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piperacillin-tazobactam 2.25 gram intravenous solution
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piperacillin-tazobactam 40.5 gram intravenous solution
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piperacillin-tazobactam 4.5 gram intravenous solution
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piperacillin-tazobactam 2.25 gram intravenous solution
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piperacillin-tazobactam 3.375 gram intravenous solution
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piperacillin-tazobactam 4.5 gram intravenous solution
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piperacillin-tazobactam 40.5 gram intravenous solution
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piperacillin-tazobactam 40.5 gram intravenous solution

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piperacillin-tazobactam 2.25 gram intravenous solution
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piperacillin-tazobactam 13.5 gram intravenous solution
piperacillin-tazobactam 13.5 gram intravenous solution

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This medicine is a colorless, clear, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

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This medicine is a colorless, clear, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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This medicine is a colorless, clear, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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This medicine is a yellow, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

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This medicine is a colorless, clear, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

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colorless
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No data.
This medicine is a colorless, clear, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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yellow
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This medicine is a yellow, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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yellow
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This medicine is a yellow, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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This medicine is a colorless, clear, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

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This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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white
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This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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yellow
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This medicine is a yellow, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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colorless
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This medicine is a colorless, clear, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

color
white
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No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
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No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

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This medicine is a white, vial
piperacillin-tazobactam 40.5 gram intravenous solution
piperacillin-tazobactam 40.5 gram intravenous solution

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This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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white
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imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
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imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
No data.
shape
No data.
imprint
No data.
This medicine is a vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 40.5 gram intravenous solution
piperacillin-tazobactam 40.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

color
colorless
shape
No data.
imprint
No data.
This medicine is a colorless, clear, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 40.5 gram intravenous solution
piperacillin-tazobactam 40.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 3.375 gram intravenous solution
piperacillin-tazobactam 3.375 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 4.5 gram intravenous solution
piperacillin-tazobactam 4.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 40.5 gram intravenous solution
piperacillin-tazobactam 40.5 gram intravenous solution

color
white
shape
No data.
imprint
No data.
This medicine is a white, vial
piperacillin-tazobactam 2.25 gram intravenous solution
piperacillin-tazobactam 2.25 gram intravenous solution

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This medicine is a white, vial

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Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.