ZOSYN Side Effects by Likelihood and Severity

COMMON side effects

If experienced, these tend to have a Severe expression i

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If experienced, these tend to have a Less Severe expression i

  • constipation
  • difficulty sleeping
  • headache
  • nausea
  • diarrhea

    • INFREQUENT side effects

    If experienced, these tend to have a Severe expression i

  • itching
  • hives
  • a skin rash
  • a significant type of allergic reaction called anaphylaxis
  • inflammation of the vein, or phlebitis after infusion

    • If experienced, these tend to have a Less Severe expression i

  • an infection due to the fungus Candida
  • vomiting
  • intense abdominal pain

    • RARE side effects

    If experienced, these tend to have a Severe expression i

  • diarrhea from an infection with Clostridium difficile bacteria
  • low blood sugar
  • a type of blood disorder where the red blood cells burst called hemolytic anemia
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • anemia
  • increased risk of bleeding due to clotting disorder
  • a change in blood platelet function
  • decreased blood platelets
  • very low levels of granulocytes, a type of white blood cell
  • low levels of white blood cells
  • low levels of a type of white blood cell called neutrophils
  • increased eosinophils in the blood
  • increase in the number of platelets in the blood
  • thrombophlebitis, an inflamed vein due to a blood clot
  • low blood pressure
  • pneumonia with high amount of eosinophil white blood cells
  • inflammation of the liver called hepatitis
  • a type of kidney inflammation called interstitial nephritis
  • kidney failure
  • erythema multiforme, a type of allergic skin reaction
  • a skin disorder with blistering and peeling skin called toxic epidermal necrolysis
  • a skin disorder with blistering and peeling skin called Stevens-Johnson syndrome
  • skin rash with sloughing
  • seizures
  • muscles to feel relaxed
  • high amount of bilirubin in the blood
  • a hypersensitivity reaction to a drug
  • a yellowing of the eyes or skin from buildup of bilirubin called jaundice
  • a type of skin disorder called acute generalized exanthematous pustulosis
  • a type of significant allergic skin reaction called DRESS syndrome
  • a high alanine transaminase level
  • a high aspartate transaminase level
  • increased alkaline phosphatase

    • If experienced, these tend to have a Less Severe expression i

  • large purple or brown skin blotches
  • stomatitis, a condition with painful swelling and sores inside the mouth
  • indigestion
  • joint pain
  • muscle pain
  • chills
  • temporary redness of face and neck
  • nosebleed
  • reactions at the site of the injection
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    Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

    CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.